Prognostic Value of Combined Detection of Serum IL6, YKL-40, and C-reactive Protein in Patients with Unresectable Pancreatic Cancer

IL6 and YKL-40 (also known as chitinase 3-like 1 protein, CHI3L1) are produced by pancreatic cancer cells and macrophages and activate inflammation. C-reactive protein (CRP) is synthesized mainly in hepatic cells and primarily stimulated by IL6. The aim of this study was to determine the prognostic...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2020-01, Vol.29 (1), p.176-184
Hauptverfasser:	Chen, Inna M, Johansen, Astrid Z, Dehlendorff, Christian, Jensen, Benny V, Bojesen, Stig E, Pfeiffer, Per, Bjerregaard, Jon K, Nielsen, Svend Erik, Andersen, Fahimeh, Holländer, Niels H, Yilmaz, Mette K, Rasmussen, Louise S, Johansen, Julia S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biomarkers, Tumor - blood C-Reactive Protein - analysis Chitinase-3-Like Protein 1 - blood Denmark - epidemiology Disease Progression Female Follow-Up Studies Humans Inflammation - blood Inflammation - diagnosis Inflammation - immunology Interleukin-6 - blood Kaplan-Meier Estimate Male Middle Aged Neoplasm Staging Palliative Care - methods Pancreatic Neoplasms - blood Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - immunology Pancreatic Neoplasms - mortality Prognosis Prospective Studies Time Factors
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