Hyperlipidemia induces meibomian gland dysfunction

To investigate the pathological changes of the meibomian gland (MG) and ocular surface in Apolipoprotein E knockout (ApoE−/−) mice and to investigate the association of meibomian gland dysfunction (MGD) with hyperlipidemia. Total plasma cholesterol was measured in different ages of ApoE−/− and wild...

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Veröffentlicht in:	The ocular surface 2019-10, Vol.17 (4), p.777-786
Hauptverfasser:	Bu, Jinghua, Wu, Yang, Cai, Xiaoxin, Jiang, Nan, Jeyalatha, M. Vimalin, Yu, Jingwen, He, Xin, He, Hui, Guo, Yuli, Zhang, Mingjie, Quantock, Andrew J., Liu, Zuguo, Li, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoprotein E Apolipoproteins E - biosynthesis Apolipoproteins E - blood Apolipoproteins E - genetics Blotting, Western Disease Models, Animal Gene Expression Regulation Hyperlipidemia Hyperlipidemias - complications Hyperlipidemias - metabolism Inflammation Male Meibomian gland dysfunction Meibomian Gland Dysfunction - diagnosis Meibomian Gland Dysfunction - etiology Meibomian Gland Dysfunction - metabolism Meibomian Glands - metabolism Meibomian Glands - pathology Mice Mice, Knockout PPAR-γ Rabbits RNA - genetics
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