Valuing Health State: An EQ-5D-5L Value Set for Ethiopians

There is a growing interest in health technology assessment and economic evaluations in developing countries such as Ethiopia. The objective of this study was to derive an EQ-5D-5L value set from the Ethiopian general population to facilitate cost utility analysis. A nationally representative sample...

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Veröffentlicht in:Value in health regional issues 2020-09, Vol.22, p.7-14
Hauptverfasser: Welie, Abraham G., Gebretekle, Gebremedhin Beedemariam, Stolk, Elly, Mukuria, Clara, Krahn, Murray D., Enquoselassie, Fikre, Fenta, Teferi Gedif
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container_end_page 14
container_issue
container_start_page 7
container_title Value in health regional issues
container_volume 22
creator Welie, Abraham G.
Gebretekle, Gebremedhin Beedemariam
Stolk, Elly
Mukuria, Clara
Krahn, Murray D.
Enquoselassie, Fikre
Fenta, Teferi Gedif
description There is a growing interest in health technology assessment and economic evaluations in developing countries such as Ethiopia. The objective of this study was to derive an EQ-5D-5L value set from the Ethiopian general population to facilitate cost utility analysis. A nationally representative sample (N = 1050) was recruited using a stratified multistage quota sampling technique. Face-to-face, computer-assisted interviews using the EuroQol Portable Valuation Technology (EQ-PVT) protocol of composite time trade-off (c-TTO) and discrete choice experiments (DCEs) were undertaken to elicit preference scores. The feasibility of the EQ-PVT protocol was pilot tested in a sample of the population (n = 110). A hybrid regression model combining c-TTO and DCE data was used to estimate the final value set. In the pilot study, the acceptability of the tasks was good, and there were no special concerns with undertaking the c-TTO and DCE tasks. The coefficients generated from a hybrid model were logically consistent. The predicted values for the EQ-5D-5L ranged from −0.718 to 1. Level 5 anxiety/depression had the largest impact on utility decrement (−0.458), whereas level 5 self-care had the least impact (−0.222). The maximum predicted value beyond full health was 0.974 for the 11112 health state. This is the first EQ-5D-5L valuation study in Africa using international valuation methods (c-TTO and DCE) and also the first using the EQ-PVT protocol to derive a value set. We expect that the availability of this value set will facilitate health technology assessment and health-related quality-of-life research and inform policy decision making in Ethiopia. •There is a growing interest in health technology assessment and economic evaluation in low-resource settings such as Ethiopia.•This study developed a value set for the EQ-5D-5L using an Ethiopian general population sample with the EuroQol Group–Portable Valuation Technology (EQ-PVT) protocol administered in Amharic.•The new value set provides local users with societal preferences that are relevant.•The study also established the feasibility of using the less resource-intensive EQ-PVT, which is relevant for future studies.
doi_str_mv 10.1016/j.vhri.2019.08.475
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Level 5 anxiety/depression had the largest impact on utility decrement (−0.458), whereas level 5 self-care had the least impact (−0.222). The maximum predicted value beyond full health was 0.974 for the 11112 health state. This is the first EQ-5D-5L valuation study in Africa using international valuation methods (c-TTO and DCE) and also the first using the EQ-PVT protocol to derive a value set. 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Level 5 anxiety/depression had the largest impact on utility decrement (−0.458), whereas level 5 self-care had the least impact (−0.222). The maximum predicted value beyond full health was 0.974 for the 11112 health state. This is the first EQ-5D-5L valuation study in Africa using international valuation methods (c-TTO and DCE) and also the first using the EQ-PVT protocol to derive a value set. 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The objective of this study was to derive an EQ-5D-5L value set from the Ethiopian general population to facilitate cost utility analysis. A nationally representative sample (N = 1050) was recruited using a stratified multistage quota sampling technique. Face-to-face, computer-assisted interviews using the EuroQol Portable Valuation Technology (EQ-PVT) protocol of composite time trade-off (c-TTO) and discrete choice experiments (DCEs) were undertaken to elicit preference scores. The feasibility of the EQ-PVT protocol was pilot tested in a sample of the population (n = 110). A hybrid regression model combining c-TTO and DCE data was used to estimate the final value set. In the pilot study, the acceptability of the tasks was good, and there were no special concerns with undertaking the c-TTO and DCE tasks. The coefficients generated from a hybrid model were logically consistent. The predicted values for the EQ-5D-5L ranged from −0.718 to 1. Level 5 anxiety/depression had the largest impact on utility decrement (−0.458), whereas level 5 self-care had the least impact (−0.222). The maximum predicted value beyond full health was 0.974 for the 11112 health state. This is the first EQ-5D-5L valuation study in Africa using international valuation methods (c-TTO and DCE) and also the first using the EQ-PVT protocol to derive a value set. 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source MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Cross-Sectional Studies
discrete choice experiment
EQ-5D-5L
Ethiopia
health state valuation
Health Status
Humans
Pilot Projects
Psychometrics - instrumentation
Psychometrics - methods
Psychometrics - standards
Quality of Life - psychology
Reproducibility of Results
time trade-off
Translating
title Valuing Health State: An EQ-5D-5L Value Set for Ethiopians
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