Multi-well plate cell contraction assay detects negatively correlated cellular responses to pharmacological inhibitors in contractility and migration

To enable large-scale screening of signaling molecules and drugs that regulate cellular contractility-associated mechanotransduction, we previously modified, particularly in terms of the capability of efficiently collecting big data, conventional methodologies using wrinkled substrates to determine...

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Veröffentlicht in:	Biochemical and biophysical research communications 2020-01, Vol.521 (2), p.527-532
Hauptverfasser:	Nehwa, Foncham Jermia, Matsui, Tsubasa S., Honghan, Li, Matsunaga, Daiki, Sakaguchi, Yoshiyuki, Deguchi, Shinji
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell assay Cell contractility Deep learning High-throughput screening Mechanobiology
Online-Zugang:	Volltext
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