Expression of PD-1/PD-L1 in head and neck squamous cell carcinoma and its clinical significance

Objective: To investigate the role of programmed death-1 (PD-1), programmed death-ligand 1 (PD-L1), and P16 in patients with head and neck squamous cell carcinoma (HNSCC). Methods: A total of 95 paraffin-embedded samples of tumorous tissue of HNSCC were collected. Expression levels of PD-1, PD-L1, a...

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Veröffentlicht in:	The International journal of biological markers 2019-12, Vol.34 (4), p.398-405
Hauptverfasser:	Chen, Shu-Wei, Li, Si-Hao, Shi, Ding-Bo, Jiang, Wen-Mei, Song, Ming, Yang, An-Kui, Li, Yu-Dong, Bei, Jin-Xin, Chen, Wen-Kuan, Zhang, Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis B7-H1 Antigen - biosynthesis B7-H1 Antigen - immunology Clinical significance Female Head & neck cancer Head and Neck Neoplasms - genetics Head and Neck Neoplasms - immunology Head and Neck Neoplasms - mortality Head and Neck Neoplasms - pathology Human papillomavirus Humans Immunohistochemistry Immunotherapy Male Medical prognosis Metastases Middle Aged Multivariate analysis Paraffin PD-1 protein PD-L1 protein Prognosis Programmed Cell Death 1 Receptor - biosynthesis Programmed Cell Death 1 Receptor - immunology Risk factors Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - genetics Squamous Cell Carcinoma of Head and Neck - immunology Squamous Cell Carcinoma of Head and Neck - mortality Survival Analysis
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