Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues

N6-methyladenosine (m6A), the most abundant internal mRNA modification, and N6,2′-O-dimethyladenosine (m6Am), found at the first-transcribed nucleotide, are two reversible epitranscriptomic marks. However, the profiles and distribution patterns of m6A and m6Am across human and mouse tissues are poor...

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Veröffentlicht in:	Molecular cell 2020-01, Vol.77 (2), p.426-440.e6
Hauptverfasser:	Liu, Jun’e, Li, Kai, Cai, Jiabin, Zhang, Mingchang, Zhang, Xiaoting, Xiong, Xushen, Meng, Haowei, Xu, Xizhan, Huang, Zhibin, Peng, Jinying, Fan, Jia, Yi, Chengqi
Format:	Artikel
Sprache:	eng
Schlagworte:	cross-species conservation epitranscriptome analysis m6A m6Am tissue specificity
Online-Zugang:	Volltext
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