Comparison of plasma, saliva, and hair lamotrigine concentrations

In some clinical situations (pregnancy, aging, drug resistance, toxicity), measurements of lamotrigine plasma levels may be reliable. Limited studies indicate that saliva and hair could be alternative sources for monitoring lamotrigine therapy. The drug content in hair can also be used to assess the...

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Veröffentlicht in:	Clinical biochemistry 2019-12, Vol.74, p.24-30
Hauptverfasser:	Kuczynska, Julita, Karas-Ruszczyk, Katarzyna, Zakrzewska, Alicja, Dermanowski, Michał, Sienkiewicz-Jarosz, Halina, Kurkowska-Jastrzebska, Iwona, Bienkowski, Przemysław, Konopko, Magdalena, Dominiak, Monika, Mierzejewski, Paweł
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anticonvulsants - administration & dosage Anticonvulsants - analysis Anticonvulsants - blood Anticonvulsants - therapeutic use Chromatography, Liquid Drug Monitoring - methods Epilepsy Epilepsy - blood Epilepsy - drug therapy Female Hair Hair - chemistry Humans Lamotrigine Lamotrigine - administration & dosage Lamotrigine - analysis Lamotrigine - blood Lamotrigine - therapeutic use Male Middle Aged Plasma Poland Saliva Saliva - chemistry Seizures - blood Seizures - drug therapy Tandem Mass Spectrometry Young Adult
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