PD-1 and PD-L1 inhibitors in oesophago-gastric cancers

Oesophago-gastric cancers (OGCs) are aggressive tumours. While better peri-operative strategies, increased number of cytotoxic agents and availability of targeted therapies have improved survival, there remains an unmet need for novel treatment approaches. Immune checkpoint inhibitors (ICIs) have ma...

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Veröffentlicht in:	Cancer letters 2020-01, Vol.469, p.142-150
Hauptverfasser:	Akin Telli, Tugba, Bregni, Giacomo, Camera, Silvia, Deleporte, Amelie, Hendlisz, Alain, Sclafani, Francesco
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer therapies Chemotherapy Clinical trials Cytotoxic agents Cytotoxicity Disease Gastric cancer Immune checkpoint inhibitors Immune response Immunomodulation Immunotherapy Inhibitors Ligands Lymphocytes Monoclonal antibodies Oesophageal-gastric cancer PD-1 PD-1 protein PD-L1 PD-L1 protein Regulatory agencies Solid tumors Tumors
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