New moonlighting functions of mitochondrial cytochrome c in the cytoplasm and nucleus

Cytochrome c (Cc) is a protein that functions as an electron carrier in the mitochondrial respiratory chain. However, Cc has moonlighting roles outside mitochondria driving the transition of apoptotic cells from life to death. When living cells are damaged, Cc escapes its natural mitochondrial envir...

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Veröffentlicht in:	FEBS letters 2019-11, Vol.593 (22), p.3101-3119
Hauptverfasser:	González‐Arzola, Katiuska, Velázquez‐Cruz, Alejandro, Guerra‐Castellano, Alejandra, Casado‐Combreras, Miguel Á., Pérez‐Mejías, Gonzalo, Díaz‐Quintana, Antonio, Díaz‐Moreno, Irene, De la Rosa, Miguel Á.
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis apoptosome caspase chromatin dynamics cytochrome c DNA damage response double‐strand break histone chaperones nuclear import programmed cell death
Online-Zugang:	Volltext
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