Sensitive determination of the human epidermal growth factor receptor 2 (HER2) by immuno-polymerase chain reaction with inductively coupled plasma-mass spectrometry detection

Sensitive and selective analytical methods are necessary for the determination of clinical biomarkers of breast cancer. The human epidermal growth factor receptor 2 (HER2) is an important breast cancer biomarker since tumors with HER2 protein overexpression (HER2-positive tumors) turn out to be more...

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Veröffentlicht in:	Analytica chimica acta 2019-12, Vol.1090, p.39-46
Hauptverfasser:	Asensio, A. Fernández, Sierra, L.M., Montes-Bayón, M., Blanco-González, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - immunology Biomarkers, Tumor - blood Biomarkers, Tumor - immunology Biotin - chemistry Breast Neoplasms - diagnosis Cancer biomarker Cell Line, Tumor DNA - chemistry ELISA HER2 ECD Humans ICP-MS Immuno-PCR Immunoassay - methods Limit of Detection Mass Spectrometry - methods Polymerase Chain Reaction - methods Receptor, ErbB-2 - blood Receptor, ErbB-2 - immunology Streptavidin - chemistry
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