Hepatitis B virus‐related hepatocellular carcinoma in young adults: Efficacy of nationwide selective vaccination

Hepatitis B virus‐related hepatocellular carcinoma in young adults: Efficacy of nationwide selective vaccination

Aim Hepatitis B vaccination in infancy was carried out in Japan only when the mother was persistently infected from 1986 to 2016. The aim of the present study was to elucidate the results of vaccination for the prevention of hepatocellular carcinoma in young adults. Methods We studied the number of...

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Veröffentlicht in:Hepatology research 2020-02, Vol.50 (2), p.182-189
Hauptverfasser: Yotsuyanagi, Hiroshi, Takano, Tomoko, Tanaka, Motofumi, Amano, Keisuke, Imamura, Michio, Ogawa, Koji, Yasunaka, Tetsuya, Yasui, Yutaka, Hayashi, Kazuhiko, Tanaka, Yasuhito, Tajiri, Hitoshi
Format: Artikel
Sprache:eng
Schlagworte:
Cirrhosis
Health risk assessment
Hepatitis
Hepatitis B
hepatitis B virus
Hepatocellular carcinoma
Immunization
Liver cancer
Liver cirrhosis
selective vaccination
Vaccination
Young adults
α‐fetoprotein
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Zusammenfassung:Aim Hepatitis B vaccination in infancy was carried out in Japan only when the mother was persistently infected from 1986 to 2016. The aim of the present study was to elucidate the results of vaccination for the prevention of hepatocellular carcinoma in young adults. Methods We studied the number of patients who had liver cancer and died from 1976 to 2017 using a national database. Furthermore, we carried out a nationwide survey focusing on patients with hepatitis B virus‐related hepatocellular carcinoma who were diagnosed when aged
ISSN:1386-6346
1872-034X
DOI:10.1111/hepr.13439