Top-down mass spectrometry of histone modifications in sorghum reveals potential epigenetic markers for drought acclimation

•A top-down mass spectrometry workflow for profiling sorghum histone was presented.•Histone modifications in sorghum under different watering conditions were studied.•An unusual pyruvic acid modification was putatively identified on H2A proteoforms.•Terminal clippings of several histones changed sig...

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Veröffentlicht in:	Methods (San Diego, Calif.) Calif.), 2020-12, Vol.184, p.29-39
Hauptverfasser:	Zhou, Mowei, Malhan, Neha, Ahkami, Amir H., Engbrecht, Kristin, Myers, Gabriel, Dahlberg, Jeffery, Hollingsworth, Joy, Sievert, Julie A., Hutmacher, Robert, Madera, Mary, Lemaux, Peggy G., Hixson, Kim K., Jansson, Christer, Paša-Tolić, Ljiljana
Format:	Artikel
Sprache:	eng
Schlagworte:	Drought Epigenetics Histone clipping Post-translational modifications Sorghum Top-down mass spectrometry
Online-Zugang:	Volltext
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