Association of MFSD3 promoter methylation level and weight regain after gastric bypass: Assessment for 3 y after surgery

•Major facilitator superfamily domain 3 (MFSD3) has been recently associated with nutrient intake and adipose tissue homeostasis.•Weight regain after bariatric surgery was positively correlated with cg00010266 MFSD3 preoperative methylation levels. Genetic predisposition and epigenetic signatures co...

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Veröffentlicht in:	Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2020-02, Vol.70, p.110499-110499, Article 110499
Hauptverfasser:	Nicoletti, Carolina F., Pinhel, Marcela S., Noronha, Natalia Y., Jácome, Amalia, Crujeiras, Ana B., Nonino, Carla Barbosa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adult Anthropometry Bisulfite Body Mass Index Body size Bypasses Correlation analysis Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics Evaluation Female Food intake Gastric Bypass Gastrointestinal surgery Genetic Predisposition to Disease - genetics Homeostasis Humans Kinases Leukocytes Levels Longitudinal Studies Membrane Transport Proteins - genetics Membrane-bound solute carriers Methylation MFSD3 gene Middle Aged Obesity Obesity - genetics Obesity - surgery Postoperative Period Promoter Regions, Genetic Roux-en-Y gastric bypass Statistical analysis Surgery Time Factors Treatment Outcome Variance analysis Weight Weight Gain - genetics Weight regain
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