Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis

The enzyme protochlorophyllide oxidoreductase (POR) catalyses a light-dependent step in chlorophyll biosynthesis that is essential to photosynthesis and, ultimately, all life on Earth 1 – 3 . POR, which is one of three known light-dependent enzymes 4 , 5 , catalyses reduction of the photosensitizer...

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Veröffentlicht in:	Nature (London) 2019-10, Vol.574 (7780), p.722-725
Hauptverfasser:	Zhang, Shaowei, Heyes, Derren J., Feng, Lingling, Sun, Wenli, Johannissen, Linus O., Liu, Huanting, Levy, Colin W., Li, Xuemei, Yang, Ji, Yu, Xiaolan, Lin, Min, Hardman, Samantha J. O., Hoeven, Robin, Sakuma, Michiyo, Hay, Sam, Leys, David, Rao, Zihe, Zhou, Aiwu, Cheng, Qi, Scrutton, Nigel S.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/535 631/57 82 Biochemistry Biosynthesis Catalysis Chemical properties Chlorophyll Chlorophyll - biosynthesis Chlorophyll - chemistry Computer simulation Crystal structure Cyanobacteria Dehydrogenases Elongated structure Enzymes Humanities and Social Sciences Life on Earth Light Methods Molecular Structure multidisciplinary NADP NADPH Nicotinamide Observations Optical properties Oxidoreductase Oxidoreductases Acting on CH-CH Group Donors - chemistry Oxidoreductases Acting on CH-CH Group Donors - metabolism Photocatalysis Photochemicals Photochemistry Photosensitization Photosynthesis Physiological aspects Proteins Protochlorophyllide Protochlorophyllide - metabolism Protons Reduction Science Science (multidisciplinary) Solvents Structural models Structure Structure-Activity Relationship Substrate Specificity Substrates Synechococcus - enzymology Synechocystis - enzymology
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