The rate of bone loss slows after 1–2 years of initial antiretroviral therapy: final results of the Strategic Timing of Antiretroviral Therapy (START) bone mineral density substudy

Objectives Initial antiretroviral therapy (ART) causes loss of bone mineral density (BMD) over the first 1–2 years. Whether this loss continues with longer therapy is unclear. We determined changes in bone and spine BMD over 5 years in adults receiving immediate or deferred initial ART. Methods In t...

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Veröffentlicht in:	HIV medicine 2020-01, Vol.21 (1), p.64-70
Hauptverfasser:	Carr, A, Grund, B, Schwartz, AV, Avihingsanon, A, Badal‐Faesen, S, Bernadino, JI, Estrada, V, La Rosa, A, Mallon, PWG, Pujari, S, White, D, Wyman Engen, N, Ensrud, K, Hoy, JF
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Biomedical materials Bone density Bone loss Bone mineral density CD4 antigen clinical trial Confidence intervals Drug therapy Energy measurement Fractures Hip HIV Human immunodeficiency virus Spine Spine (lumbar) Surgical implants Therapy
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