Functional dopaminergic neurons derived from human chorionic mesenchymal stem cells ameliorate striatal atrophy and improve behavioral deficits in Parkinsonian rat model

Human chorionic mesenchymal stem cells (HCMSCs) have been recognized as a desirable choice for cell therapy in neurological disorders such as Parkinson's disease (PD). Due to invaluable features of HCMSCs including their immunomodulatory and immunosuppressive properties, easily accessible and l...

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Veröffentlicht in:	Anatomical record (Hoboken, N.J. : 2007) N.J. : 2007), 2020-08, Vol.303 (8), p.2274-2289
Hauptverfasser:	Ebrahimi, Vahid, Eskandarian Boroujeni, Mahdi, Aliaghaei, Abbas, Abdollahifar, Mohammad Amin, Piryaei, Abbas, Haghir, Hossein, Sadeghi, Yousef
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Atrophy Basal ganglia Behavior, Animal - physiology Caspase Cell therapy Central nervous system diseases chorion Corpus Striatum - pathology Dopamine receptors dopaminergic neuron Dopaminergic Neurons - transplantation Immunocytochemistry Immunomodulation Liquid chromatography Mesenchymal stem cells Mesenchymal Stem Cells - cytology Motor Activity - physiology Movement disorders Neostriatum Neurodegenerative diseases neurodifferentiation Neurogenesis - physiology Neurological diseases Neurons Parkinson Disease, Secondary - pathology Parkinson Disease, Secondary - physiopathology Parkinson Disease, Secondary - surgery Parkinson's disease Polymerase chain reaction Rats Regenerative medicine Stem cell transplantation Stem cells stereology
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