Mutational profiling in myelofibrosis: implications for management

Mutational profiling, usually by targeted next-generation sequencing, is increasingly performed on patients with myeloproliferative neoplasm-associated myelofibrosis (MF), whether primary (PMF) or post-polycythemia vera/essential thrombocythemia (post-PV/ET MF). “Driver” mutations in JAK2, MPL and i...

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Veröffentlicht in:	International journal of hematology 2020-02, Vol.111 (2), p.192-199
Hauptverfasser:	Bose, Prithviraj, Verstovsek, Srdan
Format:	Artikel
Sprache:	eng
Schlagworte:	Calreticulin - genetics Chemotherapy Decision Making Drug therapy Genotypes Hematology Humans Janus kinase 2 Janus Kinase 2 - genetics Medical prognosis Medicine Medicine & Public Health Mutation Myelofibrosis Next-generation sequencing Oncology Polycythemia Polycythemia vera Primary Myelofibrosis - genetics Primary Myelofibrosis - therapy Progress in Hematology Receptors, Thrombopoietin - genetics
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