Chronic administration of Cl‐amidine, a pan‐peptidylarginine deiminase inhibitor, does not reverse bone loss in two different murine models of osteoporosis

Recent in vitro studies have shown a role for the peptidyl‐arginine deiminases (PADs) in bone resorption. However, it is unknown whether these enzymes are involved in bone loss in vivo. Thus, we evaluated the antiresorptive effect of a pan‐PAD inhibitor in two murine models of osteoporosis: (a) prim...

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