The (pro)renin receptor in health and disease

The (pro)renin receptor ((P)RR) was first identified as a single-transmembrane receptor in human kidneys and initially attracted attention owing to its potential role as a regulator of the tissue renin–angiotensin system (RAS). Subsequent studies found that the (P)RR is widely distributed in organs...

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Veröffentlicht in:	Nature reviews. Nephrology 2019-11, Vol.15 (11), p.693-712
Hauptverfasser:	Ichihara, Atsuhiro, Yatabe, Midori Sasaki
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4022/1585 692/420 692/699/75/243 692/699/75/243/793 Analysis Autophagy Bioenergetics Blood pressure Brain - physiology Brain - physiopathology Cardiovascular disease Care and treatment Cell cycle Chronic kidney failure Diabetes Diagnosis Embryonic development Energy metabolism Eye - physiopathology Female Health aspects Heart - physiology Heart - physiopathology Homeostasis Homeostasis - physiology Humans Hypertension Immune System - physiology Immune System - physiopathology Kidney - physiology Kidney - physiopathology Kidneys Medicine Medicine & Public Health Metabolism Methods Nephrology Ocular Physiological Phenomena Pathogenesis Phosphorylation Physiology Placenta - physiology Placenta - physiopathology Preeclampsia Pregnancy Proteins Receptors, Cell Surface - physiology Regulation Renin-angiotensin system Renin-Angiotensin System - physiology Review Article Risk factors Vacuolar Proton-Translocating ATPases - physiology
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