Aberrant DNA methylation of PAX1, SOX1 and ZNF582 genes as potential biomarkers for esophageal squamous cell carcinoma

Pyrosequencing is considered the gold standard for methylation detection. Using pyrosequencing to detect the DNA methylation statue of PAX1, SOX1 and ZNF582 in ESCC. The receiver operating characteristic curves showed that the detection of PAX1/SOX1/ZNF582 methylation status may serve as a promising...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2019-12, Vol.120, p.109488-109488, Article 109488
Hauptverfasser:	Tang, Li, Liou, Yu-Ligh, Wan, Zi-Rui, Tang, Jie, Zhou, Yuan, Zhuang, Wei, Wang, Guo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Cell Differentiation - genetics DNA methylation DNA Methylation - genetics Esophageal Neoplasms - genetics Esophageal squamous cell carcinoma Esophageal Squamous Cell Carcinoma - genetics Female Humans Kruppel-Like Transcription Factors - genetics Male Middle Aged Paired Box Transcription Factors - genetics PAX1 SOX1 SOXB1 Transcription Factors - genetics ZNF582
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