Tetramerization at Low pH Licenses DNA Methylation Activity of M.HpyAXI in the Presence of Acid Stress

Methylation of genomic DNA can influence the transcription profile of an organism and may generate phenotypic diversity for rapid adaptation in a dynamic environment. M.HpyAXI is a Type III DNA methyltransferase present in Helicobacter pylori and is upregulated at low pH. This enzyme may alter the e...

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Veröffentlicht in:	Journal of molecular biology 2020-01, Vol.432 (2), p.324-342
Hauptverfasser:	Narayanan, Naveen, Banerjee, Arun, Jain, Deepti, Kulkarni, Dhananjaya S., Sharma, Rahul, Nirwal, Shivlee, Rao, Desirazu N., Nair, Deepak T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid stress DNA methyltransferase Helicobacter pylori pH sensitive Tetramer
Online-Zugang:	Volltext
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