Terpinen-4-ol inhibits the growth of Sporothrix schenckii complex and exhibits synergism with antifungal agents

This study investigated the effect of terpinen-4-ol against complex and its interactions with antifungals. The antifungal activity of terpinen-4-ol was evaluated by broth microdilution. The potential effect on cellular ergosterol concentration was evaluated by spectrophotometry. The antibiofilm acti...

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Veröffentlicht in:	Future microbiology 2019-09, Vol.14 (14), p.1221-1233
Hauptverfasser:	Brilhante, Raimunda Sn, Pereira, Vandbergue S, Oliveira, Jonathas S, Rodrigues, Anderson M, de Camargo, Zoilo P, Pereira-Neto, Waldemiro A, Nascimento, Nilberto Rf, Castelo-Branco, Débora Scm, Cordeiro, Rossana A, Sidrim, José Jc, Rocha, Marcos Fg
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal activity Antifungal agents Antifungal Agents - pharmacology Biofilms Biofilms - drug effects Drug Synergism Drugs Ergosterol Ergosterol - analysis Experiments Fungi Itraconazole Laboratories Microbial Sensitivity Tests Microorganisms Natural products Oils & fats Potassium Spectrophotometry Sporothrix Sporothrix - drug effects Sporothrix - growth & development Sporothrix schenckii Sterols Synergism Terbinafine Terpenes - pharmacology Terpinene
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