Mathematical modelling of cancer stem cell-targeted immunotherapy

•Mathematical modelling of the interactions of cancer stem cells (CSCs), non-CSCs, cytotoxic T-cells (CTCs), and dendritic cells (DCs) to replicate the following experimental results: Grafting mice with CSCs produces more, and larger tumors than transfusing mice with nCSCs. Giving mice dendritic cel...

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Veröffentlicht in:	Mathematical biosciences 2019-12, Vol.318, p.108269-108269, Article 108269
Hauptverfasser:	Sigal, Daniel, Przedborski, Michelle, Sivaloganathan, Darshan, Kohandel, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cancer immunotherapy Cancer therapies Cell differentiation Chemotherapy Cytotoxicity Dendritic cells Differential equations Immune system Immunotherapy Lymphocytes T Mathematical analysis Mathematical modeling Mathematical models Ordinary differential equations Schedules Stem cells Tumor heterogeneity Tumorigenicity Tumors Vaccines
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