How Sugars Modify Caffeine Self-Association and Solubility: Resolving a Mechanism of Selective Hydrotropy

The aggregation of drugs and nutraceuticals in aqueous media is an outstanding problem for their efficacy and bioavailability. A common solution is to add excipients or hydrotropes that increase solubility and limit aggregation. Here we study caffeine, a widely consumed drug that undergoes oligomeri...

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Veröffentlicht in:	Journal of the American Chemical Society 2019-11, Vol.141 (45), p.18056-18063
Hauptverfasser:	Shumilin, Ilan, Allolio, Christoph, Harries, Daniel
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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