Bleeding signs due to acquired von Willebrand syndrome at diagnosis of chronic myeloid leukaemia in children

Summary A considerable proportion of patients with chronic myeloid leukaemia (CML) may present at diagnosis with high platelet counts. This may result in thrombosis or bleeding complications due to binding of von Willebrand factor (VWF) multimers to platelets. Paediatric CML is very rare and no syst...

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