Zoledronic Acid Improves Muscle Function in Healthy Mice Treated with Chemotherapy

ABSTRACT Carboplatin is a chemotherapy drug used to treat solid tumors but also causes bone loss and muscle atrophy and weakness. Bone loss contributes to muscle weakness through bone‐muscle crosstalk, which is prevented with the bisphosphonate zoledronic acid (ZA). We treated mice with carboplatin...

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