Results of chimney endovascular aneurysm repair as used in the PERICLES Registry to treat patients with suprarenal aortic pathologies

The prevailing evidence calls for using chimney/snorkel endovascular repair (ch-EVAR) with one or two chimney grafts. No studies up to now focus on its applicability and results for the treatment of suprarenal aortic pathologies (SRAP). Hence, we evaluated the clinical and radiologic results of ch-E...

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Veröffentlicht in:Journal of vascular surgery 2020-05, Vol.71 (5), p.1521-1527.e1
Hauptverfasser: Taneva, Gergana T., Criado, Frank J., Torsello, Giovanni, Veith, Frank, Scali, Salvatore T., Kubilis, Paul, Donas, Konstantinos P., Dalman, Ronald L., Tran, Kenneth, Lee, Jason, Pecoraro, Felice, Bisdas, Theodosios, Seifert, Sven, Esche, Mirko, Gasparini, Daniele, Frigatti, Paolo, Adovasio, Roberto, Mucelli, Fabio Pozzi, Damrauer, Scott M., Woo, Edward Y., Minion, David, Salenius, Juha, Suominen, Velipekka, Mangialardi, Nicola, Ronchey, Sonia, Fazzini, Stefano, Mestres, Gaspar, Riambau, Vincent, Mosquera, Nilo J.
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container_end_page 1527.e1
container_issue 5
container_start_page 1521
container_title Journal of vascular surgery
container_volume 71
creator Taneva, Gergana T.
Criado, Frank J.
Torsello, Giovanni
Veith, Frank
Scali, Salvatore T.
Kubilis, Paul
Donas, Konstantinos P.
Dalman, Ronald L.
Tran, Kenneth
Lee, Jason
Pecoraro, Felice
Bisdas, Theodosios
Seifert, Sven
Esche, Mirko
Gasparini, Daniele
Frigatti, Paolo
Adovasio, Roberto
Mucelli, Fabio Pozzi
Damrauer, Scott M.
Woo, Edward Y.
Minion, David
Salenius, Juha
Suominen, Velipekka
Mangialardi, Nicola
Ronchey, Sonia
Fazzini, Stefano
Mestres, Gaspar
Riambau, Vincent
Mosquera, Nilo J.
description The prevailing evidence calls for using chimney/snorkel endovascular repair (ch-EVAR) with one or two chimney grafts. No studies up to now focus on its applicability and results for the treatment of suprarenal aortic pathologies (SRAP). Hence, we evaluated the clinical and radiologic results of ch-EVAR treatment for SRAP placing three or more chimney grafts within the PERICLES Registry. Data from 517 patients suffering complex aortic pathologies treated by ch-EVAR between 2008 and 2014 at 13 European and U.S. centers were retrospectively reviewed and analyzed. Sixty-seven ch-EVAR-treated patients (12.9% of the entire PERICLES cohort) presented SRAP (83.5% elective, 16.5% urgent). The majority of patients (95.5%) received three chimney grafts; four patients received four chimney grafts. The Endurant device was the most commonly used (35.8%) followed by the Zenith abdominal endograft (19.4%). Overall, 204 chimney grafts were placed (56.7% covered self-expandable, 40.3% covered balloon-expandable stents, and 10.4% bare metal balloon-expandable stents). At a median follow-up of 24 months (range, 0.1-67.0 days), 30-day mortality was 6.1% (4 patients), and the overall mortality was 16.4% (11 patients). Overall survival was 87.4% (range, 79.5%-96.0%) at 1 year, 81.8% (range, 72.2%-92.2%) at 2 years and thereafter. Type IA endoleak was noted in nine patients (13.4%) intraoperatively and successfully treated in seven cases (97.1% technical success). Aneurysm sac diameter significantly decreased from 70.5 ± 19.3 mm to 66.9 ± 20.6 mm (P 
doi_str_mv 10.1016/j.jvs.2019.08.228
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No studies up to now focus on its applicability and results for the treatment of suprarenal aortic pathologies (SRAP). Hence, we evaluated the clinical and radiologic results of ch-EVAR treatment for SRAP placing three or more chimney grafts within the PERICLES Registry. Data from 517 patients suffering complex aortic pathologies treated by ch-EVAR between 2008 and 2014 at 13 European and U.S. centers were retrospectively reviewed and analyzed. Sixty-seven ch-EVAR-treated patients (12.9% of the entire PERICLES cohort) presented SRAP (83.5% elective, 16.5% urgent). The majority of patients (95.5%) received three chimney grafts; four patients received four chimney grafts. The Endurant device was the most commonly used (35.8%) followed by the Zenith abdominal endograft (19.4%). Overall, 204 chimney grafts were placed (56.7% covered self-expandable, 40.3% covered balloon-expandable stents, and 10.4% bare metal balloon-expandable stents). At a median follow-up of 24 months (range, 0.1-67.0 days), 30-day mortality was 6.1% (4 patients), and the overall mortality was 16.4% (11 patients). Overall survival was 87.4% (range, 79.5%-96.0%) at 1 year, 81.8% (range, 72.2%-92.2%) at 2 years and thereafter. Type IA endoleak was noted in nine patients (13.4%) intraoperatively and successfully treated in seven cases (97.1% technical success). Aneurysm sac diameter significantly decreased from 70.5 ± 19.3 mm to 66.9 ± 20.6 mm (P &lt; .001) at last follow-up. Ischemic stroke or transient ischemic attack were noted in two patients (2.9%). Chimney occlusion was detected in six renal arteries (9.5%) and two superior mesenteric arteries (3.2%). No patients required chronic hemodialysis. All occluded superior mesenteric artery grafts were successfully rescued using endovascular approaches. The midterm use of ch-EVAR for the treatment SRAP seems to be safe, highlighting its applicability for the treatment of rupture threatening pathologies and seal zone lengthening as in type IA endoleaks after EVAR. However, the incidence of type IA endoleaks, chimney graft occlusions, and ischemic stroke rates is higher compared with the prevailing single chimney evidence. Longer follow-up with more cases is needed to establish the exact performance of this treatment in SRAP.</description><identifier>ISSN: 0741-5214</identifier><identifier>EISSN: 1097-6809</identifier><identifier>DOI: 10.1016/j.jvs.2019.08.228</identifier><identifier>PMID: 31611110</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Aged, 80 and over ; Aortic Diseases - diagnostic imaging ; Aortic Diseases - physiopathology ; Aortic Diseases - surgery ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation - adverse effects ; Blood Vessel Prosthesis Implantation - instrumentation ; Complex aneurysms ; Endovascular Procedures - adverse effects ; Endovascular Procedures - instrumentation ; Europe ; Female ; Humans ; Male ; Mesenteric Artery, Superior - diagnostic imaging ; Mesenteric Artery, Superior - physiopathology ; Mesenteric Artery, Superior - surgery ; Multiple chimney EVAR ; Postoperative Complications - etiology ; Prosthesis Design ; Registries ; Renal Artery - diagnostic imaging ; Renal Artery - physiopathology ; Renal Artery - surgery ; Retrospective Studies ; Risk Factors ; Stents ; Superior mesenteric artery ; Suprarenal aneurysms ; Time Factors ; Treatment Outcome ; Triple chimney EVAR ; United States</subject><ispartof>Journal of vascular surgery, 2020-05, Vol.71 (5), p.1521-1527.e1</ispartof><rights>2019 Society for Vascular Surgery</rights><rights>Copyright © 2019 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-5880eb068f98d3f0b0d8f19bff89b30b07cd4087fc35ead50e4f3bc7758b06b93</citedby><cites>FETCH-LOGICAL-c396t-5880eb068f98d3f0b0d8f19bff89b30b07cd4087fc35ead50e4f3bc7758b06b93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jvs.2019.08.228$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31611110$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taneva, Gergana T.</creatorcontrib><creatorcontrib>Criado, Frank J.</creatorcontrib><creatorcontrib>Torsello, Giovanni</creatorcontrib><creatorcontrib>Veith, Frank</creatorcontrib><creatorcontrib>Scali, Salvatore T.</creatorcontrib><creatorcontrib>Kubilis, Paul</creatorcontrib><creatorcontrib>Donas, Konstantinos P.</creatorcontrib><creatorcontrib>Dalman, Ronald L.</creatorcontrib><creatorcontrib>Tran, Kenneth</creatorcontrib><creatorcontrib>Lee, Jason</creatorcontrib><creatorcontrib>Pecoraro, Felice</creatorcontrib><creatorcontrib>Bisdas, Theodosios</creatorcontrib><creatorcontrib>Seifert, Sven</creatorcontrib><creatorcontrib>Esche, Mirko</creatorcontrib><creatorcontrib>Gasparini, Daniele</creatorcontrib><creatorcontrib>Frigatti, Paolo</creatorcontrib><creatorcontrib>Adovasio, Roberto</creatorcontrib><creatorcontrib>Mucelli, Fabio Pozzi</creatorcontrib><creatorcontrib>Damrauer, Scott M.</creatorcontrib><creatorcontrib>Woo, Edward Y.</creatorcontrib><creatorcontrib>Minion, David</creatorcontrib><creatorcontrib>Salenius, Juha</creatorcontrib><creatorcontrib>Suominen, Velipekka</creatorcontrib><creatorcontrib>Mangialardi, Nicola</creatorcontrib><creatorcontrib>Ronchey, Sonia</creatorcontrib><creatorcontrib>Fazzini, Stefano</creatorcontrib><creatorcontrib>Mestres, Gaspar</creatorcontrib><creatorcontrib>Riambau, Vincent</creatorcontrib><creatorcontrib>Mosquera, Nilo J.</creatorcontrib><creatorcontrib>PERICLES collaborators</creatorcontrib><title>Results of chimney endovascular aneurysm repair as used in the PERICLES Registry to treat patients with suprarenal aortic pathologies</title><title>Journal of vascular surgery</title><addtitle>J Vasc Surg</addtitle><description>The prevailing evidence calls for using chimney/snorkel endovascular repair (ch-EVAR) with one or two chimney grafts. No studies up to now focus on its applicability and results for the treatment of suprarenal aortic pathologies (SRAP). Hence, we evaluated the clinical and radiologic results of ch-EVAR treatment for SRAP placing three or more chimney grafts within the PERICLES Registry. Data from 517 patients suffering complex aortic pathologies treated by ch-EVAR between 2008 and 2014 at 13 European and U.S. centers were retrospectively reviewed and analyzed. Sixty-seven ch-EVAR-treated patients (12.9% of the entire PERICLES cohort) presented SRAP (83.5% elective, 16.5% urgent). The majority of patients (95.5%) received three chimney grafts; four patients received four chimney grafts. The Endurant device was the most commonly used (35.8%) followed by the Zenith abdominal endograft (19.4%). Overall, 204 chimney grafts were placed (56.7% covered self-expandable, 40.3% covered balloon-expandable stents, and 10.4% bare metal balloon-expandable stents). At a median follow-up of 24 months (range, 0.1-67.0 days), 30-day mortality was 6.1% (4 patients), and the overall mortality was 16.4% (11 patients). Overall survival was 87.4% (range, 79.5%-96.0%) at 1 year, 81.8% (range, 72.2%-92.2%) at 2 years and thereafter. Type IA endoleak was noted in nine patients (13.4%) intraoperatively and successfully treated in seven cases (97.1% technical success). Aneurysm sac diameter significantly decreased from 70.5 ± 19.3 mm to 66.9 ± 20.6 mm (P &lt; .001) at last follow-up. Ischemic stroke or transient ischemic attack were noted in two patients (2.9%). Chimney occlusion was detected in six renal arteries (9.5%) and two superior mesenteric arteries (3.2%). No patients required chronic hemodialysis. All occluded superior mesenteric artery grafts were successfully rescued using endovascular approaches. The midterm use of ch-EVAR for the treatment SRAP seems to be safe, highlighting its applicability for the treatment of rupture threatening pathologies and seal zone lengthening as in type IA endoleaks after EVAR. However, the incidence of type IA endoleaks, chimney graft occlusions, and ischemic stroke rates is higher compared with the prevailing single chimney evidence. Longer follow-up with more cases is needed to establish the exact performance of this treatment in SRAP.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aortic Diseases - diagnostic imaging</subject><subject>Aortic Diseases - physiopathology</subject><subject>Aortic Diseases - surgery</subject><subject>Blood Vessel Prosthesis</subject><subject>Blood Vessel Prosthesis Implantation - adverse effects</subject><subject>Blood Vessel Prosthesis Implantation - instrumentation</subject><subject>Complex aneurysms</subject><subject>Endovascular Procedures - adverse effects</subject><subject>Endovascular Procedures - instrumentation</subject><subject>Europe</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Mesenteric Artery, Superior - diagnostic imaging</subject><subject>Mesenteric Artery, Superior - physiopathology</subject><subject>Mesenteric Artery, Superior - surgery</subject><subject>Multiple chimney EVAR</subject><subject>Postoperative Complications - etiology</subject><subject>Prosthesis Design</subject><subject>Registries</subject><subject>Renal Artery - diagnostic imaging</subject><subject>Renal Artery - physiopathology</subject><subject>Renal Artery - surgery</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Stents</subject><subject>Superior mesenteric artery</subject><subject>Suprarenal aneurysms</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Triple chimney EVAR</subject><subject>United States</subject><issn>0741-5214</issn><issn>1097-6809</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEGP0zAQhS0EYrsLP4AL8pFLwjhpEkecUFVgpUqgAmfLccZbV0kcPE5RfwD_G1dd9shcRqN570nvY-yNgFyAqN8f8-OJ8gJEm4PMi0I-YysBbZPVEtrnbAXNWmRVIdY37JboCCBEJZuX7KYUtUgDK_Znj7QMkbi33BzcOOGZ49T7kyazDDpwPeESzjTygLN26Sa-EPbcTTwekH_b7u83u-13vscHRzGcefQ8BtSRzzo6nFL0bxcPnJY56ICTHrj2ITpz-R_84B8c0iv2wuqB8PXjvmM_P21_bL5ku6-f7zcfd5kp2zpmlZSAHdTStrIvLXTQSyvazlrZdmU6G9OvQTbWlBXqvgJc27IzTVPJ5Ora8o69u-bOwf9akKIaHRkchtTSL6SKEioJAHWTpOIqNcETBbRqDm7U4awEqAt9dVSJvrrQVyBVop88bx_jl27E_snxD3cSfLgKMJU8OQyKTGJksHcBTVS9d_-J_wt9-pgU</recordid><startdate>202005</startdate><enddate>202005</enddate><creator>Taneva, Gergana T.</creator><creator>Criado, Frank J.</creator><creator>Torsello, Giovanni</creator><creator>Veith, Frank</creator><creator>Scali, Salvatore T.</creator><creator>Kubilis, Paul</creator><creator>Donas, Konstantinos P.</creator><creator>Dalman, Ronald L.</creator><creator>Tran, Kenneth</creator><creator>Lee, Jason</creator><creator>Pecoraro, Felice</creator><creator>Bisdas, Theodosios</creator><creator>Seifert, Sven</creator><creator>Esche, Mirko</creator><creator>Gasparini, Daniele</creator><creator>Frigatti, Paolo</creator><creator>Adovasio, Roberto</creator><creator>Mucelli, Fabio Pozzi</creator><creator>Damrauer, Scott M.</creator><creator>Woo, Edward Y.</creator><creator>Minion, David</creator><creator>Salenius, Juha</creator><creator>Suominen, Velipekka</creator><creator>Mangialardi, Nicola</creator><creator>Ronchey, Sonia</creator><creator>Fazzini, Stefano</creator><creator>Mestres, Gaspar</creator><creator>Riambau, Vincent</creator><creator>Mosquera, Nilo J.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202005</creationdate><title>Results of chimney endovascular aneurysm repair as used in the PERICLES Registry to treat patients with suprarenal aortic pathologies</title><author>Taneva, Gergana T. ; Criado, Frank J. ; Torsello, Giovanni ; Veith, Frank ; Scali, Salvatore T. ; Kubilis, Paul ; Donas, Konstantinos P. ; Dalman, Ronald L. ; Tran, Kenneth ; Lee, Jason ; Pecoraro, Felice ; Bisdas, Theodosios ; Seifert, Sven ; Esche, Mirko ; Gasparini, Daniele ; Frigatti, Paolo ; Adovasio, Roberto ; Mucelli, Fabio Pozzi ; Damrauer, Scott M. ; Woo, Edward Y. ; Minion, David ; Salenius, Juha ; Suominen, Velipekka ; Mangialardi, Nicola ; Ronchey, Sonia ; Fazzini, Stefano ; Mestres, Gaspar ; Riambau, Vincent ; Mosquera, Nilo J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-5880eb068f98d3f0b0d8f19bff89b30b07cd4087fc35ead50e4f3bc7758b06b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aortic Diseases - diagnostic imaging</topic><topic>Aortic Diseases - physiopathology</topic><topic>Aortic Diseases - surgery</topic><topic>Blood Vessel Prosthesis</topic><topic>Blood Vessel Prosthesis Implantation - adverse effects</topic><topic>Blood Vessel Prosthesis Implantation - instrumentation</topic><topic>Complex aneurysms</topic><topic>Endovascular Procedures - adverse effects</topic><topic>Endovascular Procedures - instrumentation</topic><topic>Europe</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Mesenteric Artery, Superior - diagnostic imaging</topic><topic>Mesenteric Artery, Superior - physiopathology</topic><topic>Mesenteric Artery, Superior - surgery</topic><topic>Multiple chimney EVAR</topic><topic>Postoperative Complications - etiology</topic><topic>Prosthesis Design</topic><topic>Registries</topic><topic>Renal Artery - diagnostic imaging</topic><topic>Renal Artery - physiopathology</topic><topic>Renal Artery - surgery</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Stents</topic><topic>Superior mesenteric artery</topic><topic>Suprarenal aneurysms</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Triple chimney EVAR</topic><topic>United States</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Taneva, Gergana T.</creatorcontrib><creatorcontrib>Criado, Frank J.</creatorcontrib><creatorcontrib>Torsello, Giovanni</creatorcontrib><creatorcontrib>Veith, Frank</creatorcontrib><creatorcontrib>Scali, Salvatore T.</creatorcontrib><creatorcontrib>Kubilis, Paul</creatorcontrib><creatorcontrib>Donas, Konstantinos P.</creatorcontrib><creatorcontrib>Dalman, Ronald L.</creatorcontrib><creatorcontrib>Tran, Kenneth</creatorcontrib><creatorcontrib>Lee, Jason</creatorcontrib><creatorcontrib>Pecoraro, Felice</creatorcontrib><creatorcontrib>Bisdas, Theodosios</creatorcontrib><creatorcontrib>Seifert, Sven</creatorcontrib><creatorcontrib>Esche, Mirko</creatorcontrib><creatorcontrib>Gasparini, Daniele</creatorcontrib><creatorcontrib>Frigatti, Paolo</creatorcontrib><creatorcontrib>Adovasio, Roberto</creatorcontrib><creatorcontrib>Mucelli, Fabio Pozzi</creatorcontrib><creatorcontrib>Damrauer, Scott M.</creatorcontrib><creatorcontrib>Woo, Edward Y.</creatorcontrib><creatorcontrib>Minion, David</creatorcontrib><creatorcontrib>Salenius, Juha</creatorcontrib><creatorcontrib>Suominen, Velipekka</creatorcontrib><creatorcontrib>Mangialardi, Nicola</creatorcontrib><creatorcontrib>Ronchey, Sonia</creatorcontrib><creatorcontrib>Fazzini, Stefano</creatorcontrib><creatorcontrib>Mestres, Gaspar</creatorcontrib><creatorcontrib>Riambau, Vincent</creatorcontrib><creatorcontrib>Mosquera, Nilo J.</creatorcontrib><creatorcontrib>PERICLES collaborators</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of vascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Taneva, Gergana T.</au><au>Criado, Frank J.</au><au>Torsello, Giovanni</au><au>Veith, Frank</au><au>Scali, Salvatore T.</au><au>Kubilis, Paul</au><au>Donas, Konstantinos P.</au><au>Dalman, Ronald L.</au><au>Tran, Kenneth</au><au>Lee, Jason</au><au>Pecoraro, Felice</au><au>Bisdas, Theodosios</au><au>Seifert, Sven</au><au>Esche, Mirko</au><au>Gasparini, Daniele</au><au>Frigatti, Paolo</au><au>Adovasio, Roberto</au><au>Mucelli, Fabio Pozzi</au><au>Damrauer, Scott M.</au><au>Woo, Edward Y.</au><au>Minion, David</au><au>Salenius, Juha</au><au>Suominen, Velipekka</au><au>Mangialardi, Nicola</au><au>Ronchey, Sonia</au><au>Fazzini, Stefano</au><au>Mestres, Gaspar</au><au>Riambau, Vincent</au><au>Mosquera, Nilo J.</au><aucorp>PERICLES collaborators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Results of chimney endovascular aneurysm repair as used in the PERICLES Registry to treat patients with suprarenal aortic pathologies</atitle><jtitle>Journal of vascular surgery</jtitle><addtitle>J Vasc Surg</addtitle><date>2020-05</date><risdate>2020</risdate><volume>71</volume><issue>5</issue><spage>1521</spage><epage>1527.e1</epage><pages>1521-1527.e1</pages><issn>0741-5214</issn><eissn>1097-6809</eissn><abstract>The prevailing evidence calls for using chimney/snorkel endovascular repair (ch-EVAR) with one or two chimney grafts. No studies up to now focus on its applicability and results for the treatment of suprarenal aortic pathologies (SRAP). Hence, we evaluated the clinical and radiologic results of ch-EVAR treatment for SRAP placing three or more chimney grafts within the PERICLES Registry. Data from 517 patients suffering complex aortic pathologies treated by ch-EVAR between 2008 and 2014 at 13 European and U.S. centers were retrospectively reviewed and analyzed. Sixty-seven ch-EVAR-treated patients (12.9% of the entire PERICLES cohort) presented SRAP (83.5% elective, 16.5% urgent). The majority of patients (95.5%) received three chimney grafts; four patients received four chimney grafts. The Endurant device was the most commonly used (35.8%) followed by the Zenith abdominal endograft (19.4%). Overall, 204 chimney grafts were placed (56.7% covered self-expandable, 40.3% covered balloon-expandable stents, and 10.4% bare metal balloon-expandable stents). At a median follow-up of 24 months (range, 0.1-67.0 days), 30-day mortality was 6.1% (4 patients), and the overall mortality was 16.4% (11 patients). Overall survival was 87.4% (range, 79.5%-96.0%) at 1 year, 81.8% (range, 72.2%-92.2%) at 2 years and thereafter. Type IA endoleak was noted in nine patients (13.4%) intraoperatively and successfully treated in seven cases (97.1% technical success). Aneurysm sac diameter significantly decreased from 70.5 ± 19.3 mm to 66.9 ± 20.6 mm (P &lt; .001) at last follow-up. Ischemic stroke or transient ischemic attack were noted in two patients (2.9%). Chimney occlusion was detected in six renal arteries (9.5%) and two superior mesenteric arteries (3.2%). No patients required chronic hemodialysis. All occluded superior mesenteric artery grafts were successfully rescued using endovascular approaches. The midterm use of ch-EVAR for the treatment SRAP seems to be safe, highlighting its applicability for the treatment of rupture threatening pathologies and seal zone lengthening as in type IA endoleaks after EVAR. However, the incidence of type IA endoleaks, chimney graft occlusions, and ischemic stroke rates is higher compared with the prevailing single chimney evidence. Longer follow-up with more cases is needed to establish the exact performance of this treatment in SRAP.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>31611110</pmid><doi>10.1016/j.jvs.2019.08.228</doi><oa>free_for_read</oa></addata></record>
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identifier ISSN: 0741-5214
ispartof Journal of vascular surgery, 2020-05, Vol.71 (5), p.1521-1527.e1
issn 0741-5214
1097-6809
language eng
recordid cdi_proquest_miscellaneous_2305800067
source MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals
subjects Aged
Aged, 80 and over
Aortic Diseases - diagnostic imaging
Aortic Diseases - physiopathology
Aortic Diseases - surgery
Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation - adverse effects
Blood Vessel Prosthesis Implantation - instrumentation
Complex aneurysms
Endovascular Procedures - adverse effects
Endovascular Procedures - instrumentation
Europe
Female
Humans
Male
Mesenteric Artery, Superior - diagnostic imaging
Mesenteric Artery, Superior - physiopathology
Mesenteric Artery, Superior - surgery
Multiple chimney EVAR
Postoperative Complications - etiology
Prosthesis Design
Registries
Renal Artery - diagnostic imaging
Renal Artery - physiopathology
Renal Artery - surgery
Retrospective Studies
Risk Factors
Stents
Superior mesenteric artery
Suprarenal aneurysms
Time Factors
Treatment Outcome
Triple chimney EVAR
United States
title Results of chimney endovascular aneurysm repair as used in the PERICLES Registry to treat patients with suprarenal aortic pathologies
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