Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteria

Atopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evaluate the clinical efficacy of HRC a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Allergologia et immunopathologia 2020-03, Vol.48 (2), p.175-181
Hauptverfasser: Akan, A., Dibek-Mısırlıoğlu, E., Civelek, E., Vezir, E., Kocabaş, C.N.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 181
container_issue 2
container_start_page 175
container_title Allergologia et immunopathologia
container_volume 48
creator Akan, A.
Dibek-Mısırlıoğlu, E.
Civelek, E.
Vezir, E.
Kocabaş, C.N.
description Atopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evaluate the clinical efficacy of HRC and UKC in pediatric age. Children diagnosed AD in the pediatric allergy clinic were enrolled. Patients with skin problems other than AD were involved as controls. All participants were evaluated for HRC and UKC at the time of diagnosis. Clinical diagnosis by the pediatric allergist was determined as the gold standard. 200 children with AD and 90 controls were enrolled in the study. Median (interquartile range, IQR) age of AD patients was 13.5 (7–36) months. There was no significant difference in age and sex between groups (p=0.11 and p=0.34, respectively). The HRC were superior to the UKC for sensitivity, negative predictive value, kappa and accuracy rate (94% vs. 72%, 84% vs. 60%, 0.68 vs. 0.56 and 87 vs. 78, respectively). On the other hand, specificity and positive predictive value of UKC were better than those of HRC (92% vs. 71% and 95% vs. 88%, respectively). HRC seem to be better in diagnosing AD than UKC for young children. Further studies are needed to evaluate comparableness of HRC and UKC for AD in childhood in order to generate an international consensus for clinical trials.
doi_str_mv 10.1016/j.aller.2019.07.008
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2305798945</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0301054619301156</els_id><sourcerecordid>2305798945</sourcerecordid><originalsourceid>FETCH-LOGICAL-c359t-959c5b0f22e69a15b877e404d130e968dea3d7822393703bcdfc83db72c6064b3</originalsourceid><addsrcrecordid>eNp9kMFu1DAQhi1ERbeFJ0BCPnJJGNuJnSBxQAVaRKVWFRVHy7EnrbeJvbWzSPv2eLuFIyePZr7fo_kIecugZsDkh3VtpglTzYH1NagaoHtBVqxVXcW4VC_JCgSwCtpGHpOTnNcAHLgUr8ixYJIxaNiK7L54cxdi9pnGkZolbrylDtNsFr-Upg_U3vvJJQwfqY3zxiSfY9jDyz3SCxP86EN1Y9YPhprgnrq3wS_o6A8f7lyc6a-YHkpJr01adtSmMkzevCZHo5kyvnl-T8ntt68_zy6qy6vz72efLysr2n6p-ra37QAj5yh7w9qhUwobaBwTgL3sHBrhVMe56IUCMVg32k64QXErQTaDOCXvD_9uUnzcYl707LPFaTIB4zZrLqBVfdc3bUHFAbUp5pxw1JvkZ5N2moHeO9dr_eRc751rULo4L6l3zwu2w4zuX-av5AJ8OgBYzvztSzxbj8Gi8wntol30_13wB3nMlEQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2305798945</pqid></control><display><type>article</type><title>Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteria</title><source>Alma/SFX Local Collection</source><creator>Akan, A. ; Dibek-Mısırlıoğlu, E. ; Civelek, E. ; Vezir, E. ; Kocabaş, C.N.</creator><creatorcontrib>Akan, A. ; Dibek-Mısırlıoğlu, E. ; Civelek, E. ; Vezir, E. ; Kocabaş, C.N.</creatorcontrib><description>Atopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evaluate the clinical efficacy of HRC and UKC in pediatric age. Children diagnosed AD in the pediatric allergy clinic were enrolled. Patients with skin problems other than AD were involved as controls. All participants were evaluated for HRC and UKC at the time of diagnosis. Clinical diagnosis by the pediatric allergist was determined as the gold standard. 200 children with AD and 90 controls were enrolled in the study. Median (interquartile range, IQR) age of AD patients was 13.5 (7–36) months. There was no significant difference in age and sex between groups (p=0.11 and p=0.34, respectively). The HRC were superior to the UKC for sensitivity, negative predictive value, kappa and accuracy rate (94% vs. 72%, 84% vs. 60%, 0.68 vs. 0.56 and 87 vs. 78, respectively). On the other hand, specificity and positive predictive value of UKC were better than those of HRC (92% vs. 71% and 95% vs. 88%, respectively). HRC seem to be better in diagnosing AD than UKC for young children. Further studies are needed to evaluate comparableness of HRC and UKC for AD in childhood in order to generate an international consensus for clinical trials.</description><identifier>ISSN: 0301-0546</identifier><identifier>EISSN: 1578-1267</identifier><identifier>DOI: 10.1016/j.aller.2019.07.008</identifier><identifier>PMID: 31611041</identifier><language>eng</language><publisher>Spain: Elsevier España, S.L.U</publisher><subject>Atopic dermatitis ; Child ; Diagnostic criteria ; Hanifin-Rajka criteria ; United Kingdom working party criteria</subject><ispartof>Allergologia et immunopathologia, 2020-03, Vol.48 (2), p.175-181</ispartof><rights>2019 SEICAP</rights><rights>Copyright © 2019 SEICAP. Published by Elsevier España, S.L.U. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-959c5b0f22e69a15b877e404d130e968dea3d7822393703bcdfc83db72c6064b3</citedby><cites>FETCH-LOGICAL-c359t-959c5b0f22e69a15b877e404d130e968dea3d7822393703bcdfc83db72c6064b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31611041$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akan, A.</creatorcontrib><creatorcontrib>Dibek-Mısırlıoğlu, E.</creatorcontrib><creatorcontrib>Civelek, E.</creatorcontrib><creatorcontrib>Vezir, E.</creatorcontrib><creatorcontrib>Kocabaş, C.N.</creatorcontrib><title>Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteria</title><title>Allergologia et immunopathologia</title><addtitle>Allergol Immunopathol (Madr)</addtitle><description>Atopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evaluate the clinical efficacy of HRC and UKC in pediatric age. Children diagnosed AD in the pediatric allergy clinic were enrolled. Patients with skin problems other than AD were involved as controls. All participants were evaluated for HRC and UKC at the time of diagnosis. Clinical diagnosis by the pediatric allergist was determined as the gold standard. 200 children with AD and 90 controls were enrolled in the study. Median (interquartile range, IQR) age of AD patients was 13.5 (7–36) months. There was no significant difference in age and sex between groups (p=0.11 and p=0.34, respectively). The HRC were superior to the UKC for sensitivity, negative predictive value, kappa and accuracy rate (94% vs. 72%, 84% vs. 60%, 0.68 vs. 0.56 and 87 vs. 78, respectively). On the other hand, specificity and positive predictive value of UKC were better than those of HRC (92% vs. 71% and 95% vs. 88%, respectively). HRC seem to be better in diagnosing AD than UKC for young children. Further studies are needed to evaluate comparableness of HRC and UKC for AD in childhood in order to generate an international consensus for clinical trials.</description><subject>Atopic dermatitis</subject><subject>Child</subject><subject>Diagnostic criteria</subject><subject>Hanifin-Rajka criteria</subject><subject>United Kingdom working party criteria</subject><issn>0301-0546</issn><issn>1578-1267</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kMFu1DAQhi1ERbeFJ0BCPnJJGNuJnSBxQAVaRKVWFRVHy7EnrbeJvbWzSPv2eLuFIyePZr7fo_kIecugZsDkh3VtpglTzYH1NagaoHtBVqxVXcW4VC_JCgSwCtpGHpOTnNcAHLgUr8ixYJIxaNiK7L54cxdi9pnGkZolbrylDtNsFr-Upg_U3vvJJQwfqY3zxiSfY9jDyz3SCxP86EN1Y9YPhprgnrq3wS_o6A8f7lyc6a-YHkpJr01adtSmMkzevCZHo5kyvnl-T8ntt68_zy6qy6vz72efLysr2n6p-ra37QAj5yh7w9qhUwobaBwTgL3sHBrhVMe56IUCMVg32k64QXErQTaDOCXvD_9uUnzcYl707LPFaTIB4zZrLqBVfdc3bUHFAbUp5pxw1JvkZ5N2moHeO9dr_eRc751rULo4L6l3zwu2w4zuX-av5AJ8OgBYzvztSzxbj8Gi8wntol30_13wB3nMlEQ</recordid><startdate>202003</startdate><enddate>202003</enddate><creator>Akan, A.</creator><creator>Dibek-Mısırlıoğlu, E.</creator><creator>Civelek, E.</creator><creator>Vezir, E.</creator><creator>Kocabaş, C.N.</creator><general>Elsevier España, S.L.U</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202003</creationdate><title>Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteria</title><author>Akan, A. ; Dibek-Mısırlıoğlu, E. ; Civelek, E. ; Vezir, E. ; Kocabaş, C.N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-959c5b0f22e69a15b877e404d130e968dea3d7822393703bcdfc83db72c6064b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Atopic dermatitis</topic><topic>Child</topic><topic>Diagnostic criteria</topic><topic>Hanifin-Rajka criteria</topic><topic>United Kingdom working party criteria</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akan, A.</creatorcontrib><creatorcontrib>Dibek-Mısırlıoğlu, E.</creatorcontrib><creatorcontrib>Civelek, E.</creatorcontrib><creatorcontrib>Vezir, E.</creatorcontrib><creatorcontrib>Kocabaş, C.N.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Allergologia et immunopathologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akan, A.</au><au>Dibek-Mısırlıoğlu, E.</au><au>Civelek, E.</au><au>Vezir, E.</au><au>Kocabaş, C.N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteria</atitle><jtitle>Allergologia et immunopathologia</jtitle><addtitle>Allergol Immunopathol (Madr)</addtitle><date>2020-03</date><risdate>2020</risdate><volume>48</volume><issue>2</issue><spage>175</spage><epage>181</epage><pages>175-181</pages><issn>0301-0546</issn><eissn>1578-1267</eissn><abstract>Atopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evaluate the clinical efficacy of HRC and UKC in pediatric age. Children diagnosed AD in the pediatric allergy clinic were enrolled. Patients with skin problems other than AD were involved as controls. All participants were evaluated for HRC and UKC at the time of diagnosis. Clinical diagnosis by the pediatric allergist was determined as the gold standard. 200 children with AD and 90 controls were enrolled in the study. Median (interquartile range, IQR) age of AD patients was 13.5 (7–36) months. There was no significant difference in age and sex between groups (p=0.11 and p=0.34, respectively). The HRC were superior to the UKC for sensitivity, negative predictive value, kappa and accuracy rate (94% vs. 72%, 84% vs. 60%, 0.68 vs. 0.56 and 87 vs. 78, respectively). On the other hand, specificity and positive predictive value of UKC were better than those of HRC (92% vs. 71% and 95% vs. 88%, respectively). HRC seem to be better in diagnosing AD than UKC for young children. Further studies are needed to evaluate comparableness of HRC and UKC for AD in childhood in order to generate an international consensus for clinical trials.</abstract><cop>Spain</cop><pub>Elsevier España, S.L.U</pub><pmid>31611041</pmid><doi>10.1016/j.aller.2019.07.008</doi><tpages>7</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0301-0546
ispartof Allergologia et immunopathologia, 2020-03, Vol.48 (2), p.175-181
issn 0301-0546
1578-1267
language eng
recordid cdi_proquest_miscellaneous_2305798945
source Alma/SFX Local Collection
subjects Atopic dermatitis
Child
Diagnostic criteria
Hanifin-Rajka criteria
United Kingdom working party criteria
title Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteria
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T21%3A16%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Diagnosis%20of%20atopic%20dermatitis%20in%20children:%20comparison%20of%20the%20Hanifin-Rajka%20and%20the%20United%20Kingdom%20Working%20Party%20criteria&rft.jtitle=Allergologia%20et%20immunopathologia&rft.au=Akan,%20A.&rft.date=2020-03&rft.volume=48&rft.issue=2&rft.spage=175&rft.epage=181&rft.pages=175-181&rft.issn=0301-0546&rft.eissn=1578-1267&rft_id=info:doi/10.1016/j.aller.2019.07.008&rft_dat=%3Cproquest_cross%3E2305798945%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2305798945&rft_id=info:pmid/31611041&rft_els_id=S0301054619301156&rfr_iscdi=true