Suppressive effect of ghrelin on nicotine-induced clock gene expression in the mouse pancreas

Those who smoke nicotine-based cigarettes have elevated plasma levels of ghrelin, a hormone secreted from the stomach. Ghrelin has various physiological functions and has recently been shown to be involved in regulating biological rhythms. Therefore, in this study, in order to clarify the significan...

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Veröffentlicht in:	ENDOCRINE JOURNAL 2020, Vol.67(1), pp.73-80
Hauptverfasser:	Sato, Takahiro, Oishi, Kanae, Ida, Takanori, Kojima, Masayasu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ARNTL Transcription Factors - drug effects ARNTL Transcription Factors - genetics Caprylates - pharmacology Cigarettes Circadian Rhythm Signaling Peptides and Proteins - drug effects Circadian Rhythm Signaling Peptides and Proteins - genetics Clock gene Clock genes CLOCK Proteins - drug effects CLOCK Proteins - genetics Cryptochromes - drug effects Cryptochromes - genetics Gastric Mucosa - drug effects Gastric Mucosa - metabolism Gene expression Gene Expression Regulation Ghrelin Ghrelin - drug effects Ghrelin - genetics Ghrelin - metabolism Glucose Transporter Type 2 - drug effects Glucose Transporter Type 2 - genetics Hypothalamus - drug effects Hypothalamus - metabolism Mice Nicotine Nicotine - administration & dosage Nicotine - pharmacology Nicotinic Agonists - administration & dosage Nicotinic Agonists - pharmacology Pancreas Pancreas - drug effects Pancreas - metabolism Period Circadian Proteins - drug effects Period Circadian Proteins - genetics Plasma levels RNA, Messenger - drug effects Stomach Stomach - drug effects
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