Anti-Phospho-Tau Gene Therapy for Chronic Traumatic Encephalopathy

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder caused by repetitive trauma to the central nervous system (CNS) suffered by soldiers, contact sport athletes, and civilians following accident-related trauma. CTE is a CNS tauopathy, with trauma-induced inflammation l...

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Veröffentlicht in:	Human gene therapy 2020-01, Vol.31 (1-2), p.57-69
Hauptverfasser:	Sacramento, Chester Bittencourt, Sondhi, Dolan, Rosenberg, Jonathan B, Chen, Alvin, Giordano, Stephanie, Pey, Eduard, Lee, Vladlena, Stiles, Katie M, Havlicek, David F, Leopold, Philip L, Kaminsky, Stephen M, Crystal, Ronald G
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Athletes Central nervous system Cerebral cortex Chronic traumatic encephalopathy Expression vectors Gene therapy Head injuries Monoclonal antibodies Neural coding Neurodegenerative diseases Neurofibrillary tangles Tau protein Trauma Traumatic brain injury Viruses
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