Trajectory and mortality of preserved ratio impaired spirometry: the Rotterdam Study

Preserved ratio impaired spirometry (PRISm) is a heterogeneous condition but its course and disease progression remain to be elucidated. We aimed to examine its prevalence, trajectories and prognosis in the general population.In the Rotterdam Study (population-based prospective cohort) we examined p...

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Veröffentlicht in:The European respiratory journal 2020-01, Vol.55 (1), p.1901217
Hauptverfasser: Wijnant, Sara Renata Alex, De Roos, Emmely, Kavousi, Maryam, Stricker, Bruno Hugo, Terzikhan, Natalie, Lahousse, Lies, Brusselle, Guy G
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Sprache:eng
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Zusammenfassung:Preserved ratio impaired spirometry (PRISm) is a heterogeneous condition but its course and disease progression remain to be elucidated. We aimed to examine its prevalence, trajectories and prognosis in the general population.In the Rotterdam Study (population-based prospective cohort) we examined prevalence, trajectories and prognosis of subjects with normal spirometry (controls; forced expiratory volume in 1 s (FEV )/forced vital capacity (FVC) ≥0.7, FEV   ≥80%), PRISm (FEV /FVC ≥0.7, FEV  
ISSN:0903-1936
1399-3003
DOI:10.1183/13993003.01217-2019