MiR-216b-5p inhibits cell proliferation in human breast cancer by down-regulating HDAC8 expression

Over-expression of histone deacetylase 8 (HDAC8) has been demonstrated in breast cancer. But the underlying molecular mechanism of HDAC8 on the progression of breast cancer remains unknown. MicroRNAs (miRs) are proposed as important molecules in cancer progression by targeting specific oncogenes or...

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Veröffentlicht in:	Life sciences (1973) 2019-11, Vol.237, p.116945-116945, Article 116945
Hauptverfasser:	Menbari, Mohammad-Nazir, Rahimi, Karim, Ahmadi, Abbas, Elyasi, Anvar, Darvishi, Nikoo, Hosseini, Vahedeh, Mohammadi-Yeganeh, Samira, Abdi, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Assaying Biotechnology Breast cancer Cancer progression Cell cycle Cell growth Cell proliferation HDAC8 Histone deacetylase Lymph nodes Metastases miR-216b-5p miRNA Overexpression Tissues Tumor cell lines Tumor suppressor genes Tumors Western blotting
Online-Zugang:	Volltext
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