Supramolecular cyclodextrin complex: Diversity, safety, and applications in ocular therapeutics

Approximately 30–70% of the existing and new chemical entities exhibit poor aqueous solubility. For topical ocular delivery, drug molecules need to possess both hydrophilic and lipophilic nature to enable absorption through the aqueous tear layer and permeation through the corneal lipophilic barrier...

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Veröffentlicht in:	Experimental eye research 2019-12, Vol.189, p.107829-107829, Article 107829
Hauptverfasser:	Chaudhari, Pinal, Ghate, Vivek M., Lewis, Shaila A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclodextrin Cyclodextrins - administration & dosage Drug Delivery Systems Eye Diseases - drug therapy Humans Inclusion complexes Mechanism Ocular diseases Ophthalmic Solutions - administration & dosage Topical delivery Toxicity Treatment Outcome
Online-Zugang:	Volltext
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