ToolBox: Live Imaging of intracellular organelle transport in induced pluripotent stem cell‐derived neurons

Induced pluripotent stem cells (iPSCs) hold promise to revolutionize studies of intracellular transport in live human neurons and to shed new light on the role of dysfunctional transport in neurodegenerative disorders. Here, we describe an approach for live imaging of axonal and dendritic transport...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2020-01, Vol.21 (1), p.138-155
Hauptverfasser:	Boecker, Clemens Alexander, Olenick, Mara A., Gallagher, Elizabeth R., Ward, Michael E., Holzbaur, Erika L. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axonal transport Axons - metabolism Biological Transport Cells, Cultured Dendritic transport Endosomes Fluorescent indicators Green fluorescent protein Hippocampus Induced Pluripotent Stem Cells Inhibitory postsynaptic potentials Intracellular iPSCs iPSC‐derived neurons live imaging Membrane proteins Mitochondria Neurodegenerative diseases Neurons NGN2 Organelles Phagosomes Pluripotency Protein turnover Rats Stem cell transplantation Stem cells Transfection Vesicles
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