Effect of cinnamon essential oil on gut microbiota in the mouse model of dextran sodium sulfate‐induced colitis
Increasing evidence has confirmed that the antimicrobial and anti‐inflammatory effects of cinnamon essential oil (CEO) contribute to protection against inflammatory bowel disease (IBD). The dextran sodium sulfate (DSS)‐induced colitis mouse model was established to investigate the correlation betwee...
Gespeichert in:
| Veröffentlicht in: | Microbiology and immunology 2020-01, Vol.64 (1), p.23-32 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 32 |
|---|---|
| container_issue | 1 |
| container_start_page | 23 |
| container_title | Microbiology and immunology |
| container_volume | 64 |
| creator | Li, Ai‐li Ni, Wei‐wei Zhang, Qi‐min Li, Ying Zhang, Xin Wu, Hong‐yan Du, Peng Hou, Jun‐cai Zhang, Yun |
| description | Increasing evidence has confirmed that the antimicrobial and anti‐inflammatory effects of cinnamon essential oil (CEO) contribute to protection against inflammatory bowel disease (IBD). The dextran sodium sulfate (DSS)‐induced colitis mouse model was established to investigate the correlation between the protective effects of CEO and the regulation of intestinal microflora. The symptoms of IBD were assessed by measuring the hemoglobin content, myeloperoxidase activity, histopathological observation, cytokines, and toll‐like receptor (TLR4) expression. The alteration of the fecal microbiome composition was analyzed by 16S rRNA gene sequencing. The results indicated that the oral administration of CEO enriched with cinnamaldehyde effectively alleviated the development of DSS‐induced colitis. In contrast to the inability of antibiotics to regulate flora imbalance, the mice fed with CEO had an improved diversity and richness of intestinal microbiota, and a modified community composition with a decrease in Helicobacter and Bacteroides and an increase in Bacteroidales_S24‐7 family and short‐chain fatty acids (SCFA)‐producing bacteria (Alloprevotella and Lachnospiraceae_NK4A136_group). Moreover, the correlation analysis showed that TLR4 and tumor necrosis factor‐α was positively correlated with Helicobacter, but inversely correlated with SCFA‐producing bacteria. These findings indicated from a new perspective that the inhibitory effect of CEO on IBD was closely related to improving the intestinal flora imbalance. |
| doi_str_mv | 10.1111/1348-0421.12749 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2303202371</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2303202371</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5029-a509a964bf234d006163ba5ce605b4978ec51da5048191cfe1c354759de56ea63</originalsourceid><addsrcrecordid>eNqFkbtOHDEUhq0IlN1sUtMhSzQ0A77OpUQrkqwEooHa8thnEqMZe3fsEaHLI-QZeZJ4WKCgwZJ9JOs7v46-g9ARJWc0n3PKRV0QwegZZZVoPqHl288BWhJey0KWhCzQlxjvCWEVq8VntOBUNlKyaol2l10HJuHQYeO810PwGGIEn5zucXD5evxrSnhwZgytC0lj53H6DXgIU5xfC_3cbuFPGrXHMVg3DThOfacTPP3957ydDFhsQu-Si1_RYaf7CN9e6grdfb-8Xf8srm5-bNYXV4WRhDWFlqTRTSnajnFhCSlpyVstDZREtqKpajCS2kyJmjbUdEANl6KSjQVZgi75Cp3uc7dj2E0QkxpcNND32kOeXDFOOCOMVzSjJ-_Q-zCNPk-XqayyZqSsM3W-p7KIGEfo1HZ0gx4fFSVq3oaa3avZvXreRu44fsmd2gHsG_-qPwNyDzy4Hh4_ylPXm-t98H9D3JSP</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2342182068</pqid></control><display><type>article</type><title>Effect of cinnamon essential oil on gut microbiota in the mouse model of dextran sodium sulfate‐induced colitis</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><source>Open Access Titles of Japan</source><source>Wiley Online Library (Open Access Collection)</source><source>Alma/SFX Local Collection</source><creator>Li, Ai‐li ; Ni, Wei‐wei ; Zhang, Qi‐min ; Li, Ying ; Zhang, Xin ; Wu, Hong‐yan ; Du, Peng ; Hou, Jun‐cai ; Zhang, Yun</creator><creatorcontrib>Li, Ai‐li ; Ni, Wei‐wei ; Zhang, Qi‐min ; Li, Ying ; Zhang, Xin ; Wu, Hong‐yan ; Du, Peng ; Hou, Jun‐cai ; Zhang, Yun</creatorcontrib><description>Increasing evidence has confirmed that the antimicrobial and anti‐inflammatory effects of cinnamon essential oil (CEO) contribute to protection against inflammatory bowel disease (IBD). The dextran sodium sulfate (DSS)‐induced colitis mouse model was established to investigate the correlation between the protective effects of CEO and the regulation of intestinal microflora. The symptoms of IBD were assessed by measuring the hemoglobin content, myeloperoxidase activity, histopathological observation, cytokines, and toll‐like receptor (TLR4) expression. The alteration of the fecal microbiome composition was analyzed by 16S rRNA gene sequencing. The results indicated that the oral administration of CEO enriched with cinnamaldehyde effectively alleviated the development of DSS‐induced colitis. In contrast to the inability of antibiotics to regulate flora imbalance, the mice fed with CEO had an improved diversity and richness of intestinal microbiota, and a modified community composition with a decrease in Helicobacter and Bacteroides and an increase in Bacteroidales_S24‐7 family and short‐chain fatty acids (SCFA)‐producing bacteria (Alloprevotella and Lachnospiraceae_NK4A136_group). Moreover, the correlation analysis showed that TLR4 and tumor necrosis factor‐α was positively correlated with Helicobacter, but inversely correlated with SCFA‐producing bacteria. These findings indicated from a new perspective that the inhibitory effect of CEO on IBD was closely related to improving the intestinal flora imbalance.</description><identifier>ISSN: 0385-5600</identifier><identifier>EISSN: 1348-0421</identifier><identifier>DOI: 10.1111/1348-0421.12749</identifier><identifier>PMID: 31595527</identifier><language>eng</language><publisher>Australia: Wiley Subscription Services, Inc</publisher><subject>16S rRNA gene sequencing ; Animals ; Antibiotics ; Bacteria ; Bacteria - classification ; Bacteria - drug effects ; Bacteria - genetics ; Bacteroides - drug effects ; Chemical composition ; Cinnamaldehyde ; Cinnamomum zeylanicum - chemistry ; Cinnamon ; cinnamon essential oil ; Colitis ; Colitis - chemically induced ; Colitis - drug therapy ; Colitis - microbiology ; Colitis - pathology ; Colon ; Community composition ; Correlation analysis ; Cytokines - metabolism ; Dextran ; dextran sodium sulfate‐induced colitis ; Dextran Sulfate - adverse effects ; Disease Models, Animal ; Essential oils ; Fatty acids ; Fatty Acids, Volatile - metabolism ; Fecal microflora ; Feces - microbiology ; Female ; Gastrointestinal Microbiome - drug effects ; Gastrointestinal Microbiome - genetics ; gut microbiota ; Helicobacter ; Helicobacter - drug effects ; Hemoglobin ; Hemoglobins ; Inflammatory bowel disease ; Inflammatory bowel diseases ; Inflammatory Bowel Diseases - drug therapy ; Inflammatory Bowel Diseases - microbiology ; Intestinal microflora ; Intestine ; Mice ; Mice, Inbred C57BL ; Microbiomes ; Microbiota ; Oils & fats ; Oils, Volatile - pharmacology ; Oral administration ; Peroxidase ; RNA, Ribosomal, 16S - genetics ; Rodents ; rRNA 16S ; Sodium sulfate ; Sulfates ; Sulfates - adverse effects ; TLR4 protein ; Toll-Like Receptor 4 - metabolism ; Toll-like receptors</subject><ispartof>Microbiology and immunology, 2020-01, Vol.64 (1), p.23-32</ispartof><rights>2019 The Societies and John Wiley & Sons Australia, Ltd</rights><rights>2019 The Societies and John Wiley & Sons Australia, Ltd.</rights><rights>2020 The Societies and John Wiley & Sons Australia, Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5029-a509a964bf234d006163ba5ce605b4978ec51da5048191cfe1c354759de56ea63</citedby><cites>FETCH-LOGICAL-c5029-a509a964bf234d006163ba5ce605b4978ec51da5048191cfe1c354759de56ea63</cites><orcidid>0000-0002-2558-8475</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2F1348-0421.12749$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2F1348-0421.12749$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,1433,27924,27925,45574,45575,46409,46833</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31595527$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Ai‐li</creatorcontrib><creatorcontrib>Ni, Wei‐wei</creatorcontrib><creatorcontrib>Zhang, Qi‐min</creatorcontrib><creatorcontrib>Li, Ying</creatorcontrib><creatorcontrib>Zhang, Xin</creatorcontrib><creatorcontrib>Wu, Hong‐yan</creatorcontrib><creatorcontrib>Du, Peng</creatorcontrib><creatorcontrib>Hou, Jun‐cai</creatorcontrib><creatorcontrib>Zhang, Yun</creatorcontrib><title>Effect of cinnamon essential oil on gut microbiota in the mouse model of dextran sodium sulfate‐induced colitis</title><title>Microbiology and immunology</title><addtitle>Microbiol Immunol</addtitle><description>Increasing evidence has confirmed that the antimicrobial and anti‐inflammatory effects of cinnamon essential oil (CEO) contribute to protection against inflammatory bowel disease (IBD). The dextran sodium sulfate (DSS)‐induced colitis mouse model was established to investigate the correlation between the protective effects of CEO and the regulation of intestinal microflora. The symptoms of IBD were assessed by measuring the hemoglobin content, myeloperoxidase activity, histopathological observation, cytokines, and toll‐like receptor (TLR4) expression. The alteration of the fecal microbiome composition was analyzed by 16S rRNA gene sequencing. The results indicated that the oral administration of CEO enriched with cinnamaldehyde effectively alleviated the development of DSS‐induced colitis. In contrast to the inability of antibiotics to regulate flora imbalance, the mice fed with CEO had an improved diversity and richness of intestinal microbiota, and a modified community composition with a decrease in Helicobacter and Bacteroides and an increase in Bacteroidales_S24‐7 family and short‐chain fatty acids (SCFA)‐producing bacteria (Alloprevotella and Lachnospiraceae_NK4A136_group). Moreover, the correlation analysis showed that TLR4 and tumor necrosis factor‐α was positively correlated with Helicobacter, but inversely correlated with SCFA‐producing bacteria. These findings indicated from a new perspective that the inhibitory effect of CEO on IBD was closely related to improving the intestinal flora imbalance.</description><subject>16S rRNA gene sequencing</subject><subject>Animals</subject><subject>Antibiotics</subject><subject>Bacteria</subject><subject>Bacteria - classification</subject><subject>Bacteria - drug effects</subject><subject>Bacteria - genetics</subject><subject>Bacteroides - drug effects</subject><subject>Chemical composition</subject><subject>Cinnamaldehyde</subject><subject>Cinnamomum zeylanicum - chemistry</subject><subject>Cinnamon</subject><subject>cinnamon essential oil</subject><subject>Colitis</subject><subject>Colitis - chemically induced</subject><subject>Colitis - drug therapy</subject><subject>Colitis - microbiology</subject><subject>Colitis - pathology</subject><subject>Colon</subject><subject>Community composition</subject><subject>Correlation analysis</subject><subject>Cytokines - metabolism</subject><subject>Dextran</subject><subject>dextran sodium sulfate‐induced colitis</subject><subject>Dextran Sulfate - adverse effects</subject><subject>Disease Models, Animal</subject><subject>Essential oils</subject><subject>Fatty acids</subject><subject>Fatty Acids, Volatile - metabolism</subject><subject>Fecal microflora</subject><subject>Feces - microbiology</subject><subject>Female</subject><subject>Gastrointestinal Microbiome - drug effects</subject><subject>Gastrointestinal Microbiome - genetics</subject><subject>gut microbiota</subject><subject>Helicobacter</subject><subject>Helicobacter - drug effects</subject><subject>Hemoglobin</subject><subject>Hemoglobins</subject><subject>Inflammatory bowel disease</subject><subject>Inflammatory bowel diseases</subject><subject>Inflammatory Bowel Diseases - drug therapy</subject><subject>Inflammatory Bowel Diseases - microbiology</subject><subject>Intestinal microflora</subject><subject>Intestine</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>Microbiomes</subject><subject>Microbiota</subject><subject>Oils & fats</subject><subject>Oils, Volatile - pharmacology</subject><subject>Oral administration</subject><subject>Peroxidase</subject><subject>RNA, Ribosomal, 16S - genetics</subject><subject>Rodents</subject><subject>rRNA 16S</subject><subject>Sodium sulfate</subject><subject>Sulfates</subject><subject>Sulfates - adverse effects</subject><subject>TLR4 protein</subject><subject>Toll-Like Receptor 4 - metabolism</subject><subject>Toll-like receptors</subject><issn>0385-5600</issn><issn>1348-0421</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkbtOHDEUhq0IlN1sUtMhSzQ0A77OpUQrkqwEooHa8thnEqMZe3fsEaHLI-QZeZJ4WKCgwZJ9JOs7v46-g9ARJWc0n3PKRV0QwegZZZVoPqHl288BWhJey0KWhCzQlxjvCWEVq8VntOBUNlKyaol2l10HJuHQYeO810PwGGIEn5zucXD5evxrSnhwZgytC0lj53H6DXgIU5xfC_3cbuFPGrXHMVg3DThOfacTPP3957ydDFhsQu-Si1_RYaf7CN9e6grdfb-8Xf8srm5-bNYXV4WRhDWFlqTRTSnajnFhCSlpyVstDZREtqKpajCS2kyJmjbUdEANl6KSjQVZgi75Cp3uc7dj2E0QkxpcNND32kOeXDFOOCOMVzSjJ-_Q-zCNPk-XqayyZqSsM3W-p7KIGEfo1HZ0gx4fFSVq3oaa3avZvXreRu44fsmd2gHsG_-qPwNyDzy4Hh4_ylPXm-t98H9D3JSP</recordid><startdate>202001</startdate><enddate>202001</enddate><creator>Li, Ai‐li</creator><creator>Ni, Wei‐wei</creator><creator>Zhang, Qi‐min</creator><creator>Li, Ying</creator><creator>Zhang, Xin</creator><creator>Wu, Hong‐yan</creator><creator>Du, Peng</creator><creator>Hou, Jun‐cai</creator><creator>Zhang, Yun</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2558-8475</orcidid></search><sort><creationdate>202001</creationdate><title>Effect of cinnamon essential oil on gut microbiota in the mouse model of dextran sodium sulfate‐induced colitis</title><author>Li, Ai‐li ; Ni, Wei‐wei ; Zhang, Qi‐min ; Li, Ying ; Zhang, Xin ; Wu, Hong‐yan ; Du, Peng ; Hou, Jun‐cai ; Zhang, Yun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5029-a509a964bf234d006163ba5ce605b4978ec51da5048191cfe1c354759de56ea63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>16S rRNA gene sequencing</topic><topic>Animals</topic><topic>Antibiotics</topic><topic>Bacteria</topic><topic>Bacteria - classification</topic><topic>Bacteria - drug effects</topic><topic>Bacteria - genetics</topic><topic>Bacteroides - drug effects</topic><topic>Chemical composition</topic><topic>Cinnamaldehyde</topic><topic>Cinnamomum zeylanicum - chemistry</topic><topic>Cinnamon</topic><topic>cinnamon essential oil</topic><topic>Colitis</topic><topic>Colitis - chemically induced</topic><topic>Colitis - drug therapy</topic><topic>Colitis - microbiology</topic><topic>Colitis - pathology</topic><topic>Colon</topic><topic>Community composition</topic><topic>Correlation analysis</topic><topic>Cytokines - metabolism</topic><topic>Dextran</topic><topic>dextran sodium sulfate‐induced colitis</topic><topic>Dextran Sulfate - adverse effects</topic><topic>Disease Models, Animal</topic><topic>Essential oils</topic><topic>Fatty acids</topic><topic>Fatty Acids, Volatile - metabolism</topic><topic>Fecal microflora</topic><topic>Feces - microbiology</topic><topic>Female</topic><topic>Gastrointestinal Microbiome - drug effects</topic><topic>Gastrointestinal Microbiome - genetics</topic><topic>gut microbiota</topic><topic>Helicobacter</topic><topic>Helicobacter - drug effects</topic><topic>Hemoglobin</topic><topic>Hemoglobins</topic><topic>Inflammatory bowel disease</topic><topic>Inflammatory bowel diseases</topic><topic>Inflammatory Bowel Diseases - drug therapy</topic><topic>Inflammatory Bowel Diseases - microbiology</topic><topic>Intestinal microflora</topic><topic>Intestine</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>Microbiomes</topic><topic>Microbiota</topic><topic>Oils & fats</topic><topic>Oils, Volatile - pharmacology</topic><topic>Oral administration</topic><topic>Peroxidase</topic><topic>RNA, Ribosomal, 16S - genetics</topic><topic>Rodents</topic><topic>rRNA 16S</topic><topic>Sodium sulfate</topic><topic>Sulfates</topic><topic>Sulfates - adverse effects</topic><topic>TLR4 protein</topic><topic>Toll-Like Receptor 4 - metabolism</topic><topic>Toll-like receptors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Ai‐li</creatorcontrib><creatorcontrib>Ni, Wei‐wei</creatorcontrib><creatorcontrib>Zhang, Qi‐min</creatorcontrib><creatorcontrib>Li, Ying</creatorcontrib><creatorcontrib>Zhang, Xin</creatorcontrib><creatorcontrib>Wu, Hong‐yan</creatorcontrib><creatorcontrib>Du, Peng</creatorcontrib><creatorcontrib>Hou, Jun‐cai</creatorcontrib><creatorcontrib>Zhang, Yun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Microbiology and immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Ai‐li</au><au>Ni, Wei‐wei</au><au>Zhang, Qi‐min</au><au>Li, Ying</au><au>Zhang, Xin</au><au>Wu, Hong‐yan</au><au>Du, Peng</au><au>Hou, Jun‐cai</au><au>Zhang, Yun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of cinnamon essential oil on gut microbiota in the mouse model of dextran sodium sulfate‐induced colitis</atitle><jtitle>Microbiology and immunology</jtitle><addtitle>Microbiol Immunol</addtitle><date>2020-01</date><risdate>2020</risdate><volume>64</volume><issue>1</issue><spage>23</spage><epage>32</epage><pages>23-32</pages><issn>0385-5600</issn><eissn>1348-0421</eissn><abstract>Increasing evidence has confirmed that the antimicrobial and anti‐inflammatory effects of cinnamon essential oil (CEO) contribute to protection against inflammatory bowel disease (IBD). The dextran sodium sulfate (DSS)‐induced colitis mouse model was established to investigate the correlation between the protective effects of CEO and the regulation of intestinal microflora. The symptoms of IBD were assessed by measuring the hemoglobin content, myeloperoxidase activity, histopathological observation, cytokines, and toll‐like receptor (TLR4) expression. The alteration of the fecal microbiome composition was analyzed by 16S rRNA gene sequencing. The results indicated that the oral administration of CEO enriched with cinnamaldehyde effectively alleviated the development of DSS‐induced colitis. In contrast to the inability of antibiotics to regulate flora imbalance, the mice fed with CEO had an improved diversity and richness of intestinal microbiota, and a modified community composition with a decrease in Helicobacter and Bacteroides and an increase in Bacteroidales_S24‐7 family and short‐chain fatty acids (SCFA)‐producing bacteria (Alloprevotella and Lachnospiraceae_NK4A136_group). Moreover, the correlation analysis showed that TLR4 and tumor necrosis factor‐α was positively correlated with Helicobacter, but inversely correlated with SCFA‐producing bacteria. These findings indicated from a new perspective that the inhibitory effect of CEO on IBD was closely related to improving the intestinal flora imbalance.</abstract><cop>Australia</cop><pub>Wiley Subscription Services, Inc</pub><pmid>31595527</pmid><doi>10.1111/1348-0421.12749</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-2558-8475</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0385-5600 |
| ispartof | Microbiology and immunology, 2020-01, Vol.64 (1), p.23-32 |
| issn | 0385-5600 1348-0421 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2303202371 |
| source | MEDLINE; Access via Wiley Online Library; Open Access Titles of Japan; Wiley Online Library (Open Access Collection); Alma/SFX Local Collection |
| subjects | 16S rRNA gene sequencing Animals Antibiotics Bacteria Bacteria - classification Bacteria - drug effects Bacteria - genetics Bacteroides - drug effects Chemical composition Cinnamaldehyde Cinnamomum zeylanicum - chemistry Cinnamon cinnamon essential oil Colitis Colitis - chemically induced Colitis - drug therapy Colitis - microbiology Colitis - pathology Colon Community composition Correlation analysis Cytokines - metabolism Dextran dextran sodium sulfate‐induced colitis Dextran Sulfate - adverse effects Disease Models, Animal Essential oils Fatty acids Fatty Acids, Volatile - metabolism Fecal microflora Feces - microbiology Female Gastrointestinal Microbiome - drug effects Gastrointestinal Microbiome - genetics gut microbiota Helicobacter Helicobacter - drug effects Hemoglobin Hemoglobins Inflammatory bowel disease Inflammatory bowel diseases Inflammatory Bowel Diseases - drug therapy Inflammatory Bowel Diseases - microbiology Intestinal microflora Intestine Mice Mice, Inbred C57BL Microbiomes Microbiota Oils & fats Oils, Volatile - pharmacology Oral administration Peroxidase RNA, Ribosomal, 16S - genetics Rodents rRNA 16S Sodium sulfate Sulfates Sulfates - adverse effects TLR4 protein Toll-Like Receptor 4 - metabolism Toll-like receptors |
| title | Effect of cinnamon essential oil on gut microbiota in the mouse model of dextran sodium sulfate‐induced colitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T23%3A47%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20cinnamon%20essential%20oil%20on%20gut%20microbiota%20in%20the%20mouse%20model%20of%20dextran%20sodium%20sulfate%E2%80%90induced%20colitis&rft.jtitle=Microbiology%20and%20immunology&rft.au=Li,%20Ai%E2%80%90li&rft.date=2020-01&rft.volume=64&rft.issue=1&rft.spage=23&rft.epage=32&rft.pages=23-32&rft.issn=0385-5600&rft.eissn=1348-0421&rft_id=info:doi/10.1111/1348-0421.12749&rft_dat=%3Cproquest_cross%3E2303202371%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2342182068&rft_id=info:pmid/31595527&rfr_iscdi=true |