LINC01342 promotes the progression of ovarian cancer by absorbing microRNA‐30c‐2‐3p to upregulate HIF3A

Ovarian cancer (OC) is a highly prevalent gynecologic malignancy and its mortality is extremely high. Therefore, the development of novel therapeutic approaches for OC is of great significance. In this study, LINC01342 was upregulated in OC tissue in the GSE38666 microarray and in tumor tissue sampl...

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Veröffentlicht in:	Journal of cellular physiology 2020-04, Vol.235 (4), p.3939-3949
Hauptverfasser:	Zhang, Chu, Liu, Jie, Zhang, Yang, Luo, Chengyan, Zhu, Tong, Zhang, Rongrong, Yao, Ruiqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Regulatory Proteins - genetics Cancer Cell Line, Tumor Cell migration Cell Movement - genetics Cell Proliferation - genetics ceRNA Cytoplasm Disease Progression DNA microarrays Female Gene Expression Regulation, Neoplastic - genetics Gene Knockdown Techniques HIF3A Humans Hypoxia Immunoprecipitation LINC01342 Malignancy Metastases MicroRNAs MicroRNAs - genetics microRNA‐30c‐2‐3p miRNA Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Repressor Proteins - genetics Ribonucleic acid RNA RNA, Long Noncoding - genetics RNA-binding protein
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