Association of maternal Toll-like receptor-4 alleles with susceptibility to early-onset preeclampsia in central Greece

•Altered maternal inflammatory responses mayconfer increased risk of early-onset preeclampsia (EOP).•Maternal TLR4Asp299GlyandThre399Ilealleles confer susceptibility to EOP.•Adjusted EOP risk ofTLR4Asp299Glycarriersis 2.94.•Adjusted EOP risk ofTLR4Thre399Ilecarriersis 3.52. Altered maternal inflamma...

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Veröffentlicht in:	Pregnancy hypertension 2019-10, Vol.18, p.103-107
Hauptverfasser:	Vamvakopoulou, Dimitra N., Satra, Maria, Fegga, Aggeliki, Kourti, Maria, Sidiropoulos, Andreas, Daponte, Alexandros, Gounaris, Antonis, Syrogiannopoulos, George, Vamvakopoulos, Nikos C., Sotiriou, Sotirios
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Case-Control Studies Early-onset preeclampsia European Continental Ancestry Group Female Gene polymorphism Genetic Predisposition to Disease Greece Humans Polymorphism, Single Nucleotide Pre-Eclampsia - blood Pre-Eclampsia - diagnosis Pre-Eclampsia - genetics Pregnancy Prenatal Diagnosis TLR4 Toll-Like Receptor 4 - genetics
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