Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect

Bipolar disorder (BD) is a highly heritable mood disorder with complex genetic architecture and poorly understood etiology. Previous transcriptomic BD studies have had inconsistent findings due to issues such as small sample sizes and difficulty in adequately accounting for confounders like medicati...

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Veröffentlicht in:	Psychological medicine 2020-11, Vol.50 (15), p.2575-2586
Hauptverfasser:	Krebs, Catharine E., Ori, Anil P.S., Vreeker, Annabel, Wu, Timothy, Cantor, Rita M., Boks, Marco P. M., Kahn, Rene S., Olde Loohuis, Loes M., Ophoff, Roel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bipolar disorder Blood Drugs Emotional disorders Etiology Gene expression Genes Genetic susceptibility Genome-wide association studies Genomes Genomics Health risk assessment Immune response Lithium Medical diagnosis Mental disorders Mood Network analysis Original Articles Principal components analysis Psychosis Psychotropic drugs Questionnaires Ribonucleic acid RNA Schizophrenia Transcriptomics
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