Development of Universal Formulation with Superior Re-dispersion Using Nanocrystal Approach with Simultaneous Identification of API Physicochemical Properties

Universal nanocrystal formulation which can be applied to water-insoluble compounds was proposed and the criteria of its physicochemical properties as an active pharmaceutical ingredients (API) were investigated. Nanocrystal suspension was prepared by a wet-beads milling method. An acceptable Critic...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 2019/10/01, Vol.67(10), pp.1050-1060
Hauptverfasser: Fujii, Hiroyuki, Watano, Satoru
Format: Artikel
Sprache:eng
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