Up‐regulation of miR‐27a promotes monocyte‐mediated inflammatory responses in Kawasaki disease by inhibiting function of B10 cells

Kawasaki disease (KD) is an acute systemic vasculitis and activation of monocytes plays a central role in the pathogenesis of it. B10 cells, a B cell subset with negative regulatory properties, are functionally identified by their ability to express cytoplasmic IL‐10 after ex vivo stimulation. Here,...

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Veröffentlicht in:Journal of leukocyte biology 2020-01, Vol.107 (1), p.133-144
Hauptverfasser: Luo, Ying, Yang, Jun, Zhang, Chi, Jin, Yan, Pan, Hong, Liu, Lanlan, Gong, Yifeng, Xia, Yu, Wang, Guobing, Zhang, Jiaosheng, Li, Chengrong, Li, Qiu
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