Morphological difference between pleural mesothelioma cells in effusion smears with either BAP1 loss or 9p21 homozygous deletion and reactive mesothelial cells without the gene alterations

We previously characterized the morphological characteristics of malignant pleural mesothelioma (MPM) cells with 9p21 homozygous deletion (HD) using a combination of the virtual microscopy and fluorescence in situ hybridization (FISH). In this study, we investigated whether MPM cells with BRCA1‐asso...

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Veröffentlicht in:	Pathology international 2019-11, Vol.69 (11), p.637-645
Hauptverfasser:	Matsumoto, Shinji, Hamasaki, Makoto, Kinoshita, Yoshiaki, Kamei, Toshiaki, Kawahara, Kunimitsu, Nabeshima, Kazuki
Format:	Artikel
Sprache:	eng
Schlagworte:	9p21 homozygous deletion BAP1 loss BRCA1 protein Breast cancer Clonal deletion Effusion effusion smear Fluorescence Fluorescence in situ hybridization Gene deletion Immunocytochemistry Mesothelioma Microscopy morphological characteristics Morphology Physical characteristics pleural mesothelioma
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