Investigation of solid tumor progression with account of proliferation/migration dichotomy via Darwinian mathematical model

A new continuous spatially-distributed model of solid tumor growth and progression is presented. The model explicitly accounts for mutations/epimutations of tumor cells which take place upon their division. The tumor grows in normal tissue and its progression is driven only by competition between po...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of mathematical biology 2020-02, Vol.80 (3), p.601-626
Hauptverfasser: Kuznetsov, Maxim, Kolobov, Andrey
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!