Behavioral responses of Ixodes scapularis tick to natural products: development of novel repellents
The spread of blacklegged ticks ( Ixodes scapularis ) and growing threat of Lyme disease transmission has increased demand for effective, safe and environmentally friendly repellent products. Plant-derived essential oils are natural products that exhibit insecticidal and repellant activities and rep...
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| Veröffentlicht in: | Experimental & applied acarology 2019-10, Vol.79 (2), p.195-207 |
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| creator | Faraone, Nicoletta MacPherson, Samantha Hillier, N. Kirk |
| description | The spread of blacklegged ticks (
Ixodes scapularis
) and growing threat of Lyme disease transmission has increased demand for effective, safe and environmentally friendly repellent products. Plant-derived essential oils are natural products that exhibit insecticidal and repellant activities and represent a promising alternative to synthetic repellants. However, mechanisms by which ticks detect odor stimuli and how such stimuli may function as repellents are not well understood. We examined the repellent activity of selected essential oil components towards
I. scapularis
in short- and long-term dose–response trials. To determine the specific olfactory organs involved in detection of chemical stimuli, we tested tick behavioral response in repellency bioassays after removing appendages that house chemosensory sensilla (e.g., foretarsi or pedipalps). New prototype formulae were tested in longevity trials repelling up to 95% of tested ticks after 1 h post-application. This study provides new insight regarding tick olfaction and behavior, and innovative methods for selecting appropriate chemicals for development of novel plant-based repellent products for protection from ticks. |
| doi_str_mv | 10.1007/s10493-019-00421-0 |
| format | Article |
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Ixodes scapularis
) and growing threat of Lyme disease transmission has increased demand for effective, safe and environmentally friendly repellent products. Plant-derived essential oils are natural products that exhibit insecticidal and repellant activities and represent a promising alternative to synthetic repellants. However, mechanisms by which ticks detect odor stimuli and how such stimuli may function as repellents are not well understood. We examined the repellent activity of selected essential oil components towards
I. scapularis
in short- and long-term dose–response trials. To determine the specific olfactory organs involved in detection of chemical stimuli, we tested tick behavioral response in repellency bioassays after removing appendages that house chemosensory sensilla (e.g., foretarsi or pedipalps). New prototype formulae were tested in longevity trials repelling up to 95% of tested ticks after 1 h post-application. This study provides new insight regarding tick olfaction and behavior, and innovative methods for selecting appropriate chemicals for development of novel plant-based repellent products for protection from ticks.</description><identifier>ISSN: 0168-8162</identifier><identifier>EISSN: 1572-9702</identifier><identifier>DOI: 10.1007/s10493-019-00421-0</identifier><identifier>PMID: 31564009</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Animal Ecology ; Animal Genetics and Genomics ; Animal Systematics/Taxonomy/Biogeography ; Animals ; Appendages ; Arachnids ; Bioassays ; Biomedical and Life Sciences ; Chemical stimuli ; Chemoreception ; Chemotaxis ; Disease transmission ; Entomology ; Essential oils ; Female ; Ixodes - drug effects ; Ixodes - growth & development ; Ixodes - physiology ; Ixodes scapularis ; Life Sciences ; Lyme disease ; Male ; Natural products ; Nymph - drug effects ; Nymph - physiology ; Odor ; Oils, Volatile - pharmacology ; Olfaction ; Olfactory organs ; Organic chemistry ; Organs ; Pedipalps ; Plant protection ; Plants ; Protective Agents - pharmacology ; Repellency ; Repellents ; Sensilla ; Stimuli ; Tick Control - methods ; Ticks ; Vector-borne diseases</subject><ispartof>Experimental & applied acarology, 2019-10, Vol.79 (2), p.195-207</ispartof><rights>Springer Nature Switzerland AG 2019</rights><rights>Experimental and Applied Acarology is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-744cfbe39127e39b75e6cec1931bbb93de2b8a116911bbf94464572ba10bc64f3</citedby><cites>FETCH-LOGICAL-c375t-744cfbe39127e39b75e6cec1931bbb93de2b8a116911bbf94464572ba10bc64f3</cites><orcidid>0000-0002-9246-3672</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10493-019-00421-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10493-019-00421-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31564009$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Faraone, Nicoletta</creatorcontrib><creatorcontrib>MacPherson, Samantha</creatorcontrib><creatorcontrib>Hillier, N. Kirk</creatorcontrib><title>Behavioral responses of Ixodes scapularis tick to natural products: development of novel repellents</title><title>Experimental & applied acarology</title><addtitle>Exp Appl Acarol</addtitle><addtitle>Exp Appl Acarol</addtitle><description>The spread of blacklegged ticks (
Ixodes scapularis
) and growing threat of Lyme disease transmission has increased demand for effective, safe and environmentally friendly repellent products. Plant-derived essential oils are natural products that exhibit insecticidal and repellant activities and represent a promising alternative to synthetic repellants. However, mechanisms by which ticks detect odor stimuli and how such stimuli may function as repellents are not well understood. We examined the repellent activity of selected essential oil components towards
I. scapularis
in short- and long-term dose–response trials. To determine the specific olfactory organs involved in detection of chemical stimuli, we tested tick behavioral response in repellency bioassays after removing appendages that house chemosensory sensilla (e.g., foretarsi or pedipalps). New prototype formulae were tested in longevity trials repelling up to 95% of tested ticks after 1 h post-application. This study provides new insight regarding tick olfaction and behavior, and innovative methods for selecting appropriate chemicals for development of novel plant-based repellent products for protection from ticks.</description><subject>Animal Ecology</subject><subject>Animal Genetics and Genomics</subject><subject>Animal Systematics/Taxonomy/Biogeography</subject><subject>Animals</subject><subject>Appendages</subject><subject>Arachnids</subject><subject>Bioassays</subject><subject>Biomedical and Life Sciences</subject><subject>Chemical stimuli</subject><subject>Chemoreception</subject><subject>Chemotaxis</subject><subject>Disease transmission</subject><subject>Entomology</subject><subject>Essential oils</subject><subject>Female</subject><subject>Ixodes - drug effects</subject><subject>Ixodes - growth & development</subject><subject>Ixodes - physiology</subject><subject>Ixodes scapularis</subject><subject>Life Sciences</subject><subject>Lyme disease</subject><subject>Male</subject><subject>Natural products</subject><subject>Nymph - drug effects</subject><subject>Nymph - physiology</subject><subject>Odor</subject><subject>Oils, Volatile - pharmacology</subject><subject>Olfaction</subject><subject>Olfactory organs</subject><subject>Organic chemistry</subject><subject>Organs</subject><subject>Pedipalps</subject><subject>Plant protection</subject><subject>Plants</subject><subject>Protective Agents - pharmacology</subject><subject>Repellency</subject><subject>Repellents</subject><subject>Sensilla</subject><subject>Stimuli</subject><subject>Tick Control - methods</subject><subject>Ticks</subject><subject>Vector-borne diseases</subject><issn>0168-8162</issn><issn>1572-9702</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kc1u1TAQhS1ERS8tL8ACRWLTTdoZx3FidlAVWqkSG7q2bMeBlNw49SQVvH3ncguVWHTjn_E3Z8ZzhHiLcIoAzRkhKFOVgKYEUBJLeCE2WDeyNA3Il2IDqNuyRS0PxWuiWwCoQdevxGGFtVYAZiPCp_jD3Q8pu7HIkeY0UaQi9cXVr9TxiYKb19HlgYplCD-LJRWTW9YdPufUrWGhD0UX7-OY5m2cll3qlPjKanMcRw7RsTjo3UjxzeN-JG4-X3w7vyyvv365Ov94XYaqqZeyUSr0PlYGZcOrb-qoQwxoKvTem6qL0rcOURvkQG-U0oo_6x2CD1r11ZE42etyZ3drpMVuBwrchJtiWslKaYziCbSG0ff_obdpzRN3t6NaIzVXYUruqZATUY69nfOwdfm3RbA7C-zeAssW2D8WWOCkd4_Sq9_G7l_K35kzUO0B4qfpe8xPtZ-RfQDvOJI9</recordid><startdate>20191001</startdate><enddate>20191001</enddate><creator>Faraone, Nicoletta</creator><creator>MacPherson, Samantha</creator><creator>Hillier, N. 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Kirk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Behavioral responses of Ixodes scapularis tick to natural products: development of novel repellents</atitle><jtitle>Experimental & applied acarology</jtitle><stitle>Exp Appl Acarol</stitle><addtitle>Exp Appl Acarol</addtitle><date>2019-10-01</date><risdate>2019</risdate><volume>79</volume><issue>2</issue><spage>195</spage><epage>207</epage><pages>195-207</pages><issn>0168-8162</issn><eissn>1572-9702</eissn><abstract>The spread of blacklegged ticks (
Ixodes scapularis
) and growing threat of Lyme disease transmission has increased demand for effective, safe and environmentally friendly repellent products. Plant-derived essential oils are natural products that exhibit insecticidal and repellant activities and represent a promising alternative to synthetic repellants. However, mechanisms by which ticks detect odor stimuli and how such stimuli may function as repellents are not well understood. We examined the repellent activity of selected essential oil components towards
I. scapularis
in short- and long-term dose–response trials. To determine the specific olfactory organs involved in detection of chemical stimuli, we tested tick behavioral response in repellency bioassays after removing appendages that house chemosensory sensilla (e.g., foretarsi or pedipalps). New prototype formulae were tested in longevity trials repelling up to 95% of tested ticks after 1 h post-application. This study provides new insight regarding tick olfaction and behavior, and innovative methods for selecting appropriate chemicals for development of novel plant-based repellent products for protection from ticks.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>31564009</pmid><doi>10.1007/s10493-019-00421-0</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-9246-3672</orcidid></addata></record> |
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| ispartof | Experimental & applied acarology, 2019-10, Vol.79 (2), p.195-207 |
| issn | 0168-8162 1572-9702 |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Animal Ecology Animal Genetics and Genomics Animal Systematics/Taxonomy/Biogeography Animals Appendages Arachnids Bioassays Biomedical and Life Sciences Chemical stimuli Chemoreception Chemotaxis Disease transmission Entomology Essential oils Female Ixodes - drug effects Ixodes - growth & development Ixodes - physiology Ixodes scapularis Life Sciences Lyme disease Male Natural products Nymph - drug effects Nymph - physiology Odor Oils, Volatile - pharmacology Olfaction Olfactory organs Organic chemistry Organs Pedipalps Plant protection Plants Protective Agents - pharmacology Repellency Repellents Sensilla Stimuli Tick Control - methods Ticks Vector-borne diseases |
| title | Behavioral responses of Ixodes scapularis tick to natural products: development of novel repellents |
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