Long‐term survival of full‐thickness corneal xenografts from α1,3‐galactosyltransferase gene‐knockout miniature pigs in non‐human primates

Background We aimed to investigate (a) the long‐term survival of corneal grafts from α1,3‐galactosyltransferase gene‐knockout miniature (GTKOm) pigs in non‐human primates as a primary outcome and (b) the effect of anti‐CD20 antibody on the survival of corneal grafts from GTKOm pigs as a secondary ou...

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Veröffentlicht in:	Xenotransplantation (Københaven) 2020-01, Vol.27 (1), p.e12559-n/a
Hauptverfasser:	Yoon, Chang Ho, Choi, Se Hyun, Choi, Hyuk Jin, Lee, Hyun Ju, Kang, Hee Jung, Kim, Jong Min, Park, Chung‐Gyu, Choi, Kimyung, Kim, Hyunil, Ahn, Curie, Kim, Mee Kum
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Antibodies, Monoclonal - therapeutic use Antigens, CD20 - immunology anti‐CD20 antibody B-Lymphocytes - physiology CD20 antigen complement Complement component C3a Cornea Corneal Transplantation Galactosyltransferases - genetics Gene Knockout Techniques Graft Rejection - prevention & control Graft Survival Heterografts - physiology Hogs Humans Immunoglobulin G Intravenous administration Lymphocyte Activation Lymphocytes B Monoclonal antibodies non‐Gal non‐human primate Primates Swine Swine, Miniature Tacrolimus Transplantation, Heterologous Xenografts xenotransplantation α1,3‐galactosyltransferase gene‐knockout miniature (GTKOm) pig
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