Glutamate, GABA, and Presynaptic Markers Involved in Neurotransmission Are Differently Affected by Age in Distinct Mouse Brain Regions

Molecular synaptic aging perturbs neurotransmission and decreases the potential for neuroplasticity. The direction and degree of changes observed in aging are often region or cell specific, hampering the generalization of age-related effects. Using real-time PCR and Western blot analyses, we investi...

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Veröffentlicht in:ACS chemical neuroscience 2019-11, Vol.10 (11), p.4449-4461
Hauptverfasser: Rozycka, Aleksandra, Charzynska, Agata, Misiewicz, Zuzanna, Maciej Stepniewski, Tomasz, Sobolewska, Alicja, Kossut, Malgorzata, Liguz-Lecznar, Monika
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Sprache:eng
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