Invasive pulmonary aspergillosis with Aspergillus vertebral osteomyelitis in an HIV-infected adult: a case report

We report the case of a 29-year-old man with human immunodeficiency virus infection and irregular adherence to antiretroviral therapy who initially presented with pulmonary symptoms and subsequently developed spinal cord compromise symptoms. After many different diagnostic tests, invasive aspergillo...

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Veröffentlicht in:International journal of STD & AIDS 2019-10, Vol.30 (11), p.1140-1142
Hauptverfasser: Senosain-Leon, Valeria, Hidalgo-Benites, Aida, Arriola-Montenegro, Jose, D’Angelo-Piaggio, Lorenzo, Beas, Renato
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container_end_page 1142
container_issue 11
container_start_page 1140
container_title International journal of STD & AIDS
container_volume 30
creator Senosain-Leon, Valeria
Hidalgo-Benites, Aida
Arriola-Montenegro, Jose
D’Angelo-Piaggio, Lorenzo
Beas, Renato
description We report the case of a 29-year-old man with human immunodeficiency virus infection and irregular adherence to antiretroviral therapy who initially presented with pulmonary symptoms and subsequently developed spinal cord compromise symptoms. After many different diagnostic tests, invasive aspergillosis with pleuroparenchymal involvement and vertebral osteomyelitis by Aspergillus spp. was diagnosed. The patient was treated with amphotericin B deoxycholate without improvement and a fatal outcome ensued. Differential diagnoses of vertebral osteomyelitis in immunosuppressed patients should be taken into account for early detection and prompt treatment.
doi_str_mv 10.1177/0956462419865403
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subjects Adult
AIDS/HIV
Antiretroviral Therapy, Highly Active
Aspergillosis - diagnosis
Aspergillosis - immunology
Aspergillosis - pathology
Aspergillus - isolation & purification
Fatal Outcome
HIV Infections - complications
HIV Infections - drug therapy
Humans
Immunocompromised Host
Invasive Pulmonary Aspergillosis
Magnetic Resonance Imaging
Male
Opportunistic Infections - complications
Opportunistic Infections - microbiology
Osteomyelitis - complications
Osteomyelitis - diagnosis
Osteomyelitis - microbiology
title Invasive pulmonary aspergillosis with Aspergillus vertebral osteomyelitis in an HIV-infected adult: a case report
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