Invasive pulmonary aspergillosis with Aspergillus vertebral osteomyelitis in an HIV-infected adult: a case report
We report the case of a 29-year-old man with human immunodeficiency virus infection and irregular adherence to antiretroviral therapy who initially presented with pulmonary symptoms and subsequently developed spinal cord compromise symptoms. After many different diagnostic tests, invasive aspergillo...
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Veröffentlicht in: | International journal of STD & AIDS 2019-10, Vol.30 (11), p.1140-1142 |
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container_title | International journal of STD & AIDS |
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creator | Senosain-Leon, Valeria Hidalgo-Benites, Aida Arriola-Montenegro, Jose D’Angelo-Piaggio, Lorenzo Beas, Renato |
description | We report the case of a 29-year-old man with human immunodeficiency virus infection and irregular adherence to antiretroviral therapy who initially presented with pulmonary symptoms and subsequently developed spinal cord compromise symptoms. After many different diagnostic tests, invasive aspergillosis with pleuroparenchymal involvement and vertebral osteomyelitis by Aspergillus spp. was diagnosed. The patient was treated with amphotericin B deoxycholate without improvement and a fatal outcome ensued. Differential diagnoses of vertebral osteomyelitis in immunosuppressed patients should be taken into account for early detection and prompt treatment. |
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After many different diagnostic tests, invasive aspergillosis with pleuroparenchymal involvement and vertebral osteomyelitis by Aspergillus spp. was diagnosed. The patient was treated with amphotericin B deoxycholate without improvement and a fatal outcome ensued. 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After many different diagnostic tests, invasive aspergillosis with pleuroparenchymal involvement and vertebral osteomyelitis by Aspergillus spp. was diagnosed. The patient was treated with amphotericin B deoxycholate without improvement and a fatal outcome ensued. Differential diagnoses of vertebral osteomyelitis in immunosuppressed patients should be taken into account for early detection and prompt treatment.</description><subject>Adult</subject><subject>AIDS/HIV</subject><subject>Antiretroviral Therapy, Highly Active</subject><subject>Aspergillosis - diagnosis</subject><subject>Aspergillosis - immunology</subject><subject>Aspergillosis - pathology</subject><subject>Aspergillus - isolation & purification</subject><subject>Fatal Outcome</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - drug therapy</subject><subject>Humans</subject><subject>Immunocompromised Host</subject><subject>Invasive Pulmonary Aspergillosis</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Opportunistic Infections - complications</subject><subject>Opportunistic Infections - microbiology</subject><subject>Osteomyelitis - complications</subject><subject>Osteomyelitis - diagnosis</subject><subject>Osteomyelitis - microbiology</subject><issn>0956-4624</issn><issn>1758-1052</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMFLwzAUh4Mobk7vniRHL9WkbZrG2xjqBgMv6rVkzevMSJsuSSf7723Z5kHw9OC97_eD9yF0S8kDpZw_EsGyNItTKvKMpSQ5Q2PKWR5RwuJzNB7O0XAfoSvvN4SQLOHiEo0SylhOYzpG20Wzk17vALedqW0j3R5L34Jba2Os1x5_6_CFp6dV5_EOXICVkwZbH8DWezA69KBusGzwfPEZ6aaCMoDCUnUmPGGJS-kBO2itC9foopLGw81xTtDHy_P7bB4t314Xs-kyKpOEh6iSgtAVcJVklJQrDkwQmSqe0ZxLJVJepSpjuWSKEZ5WJQgKIFXMSMUUVSKZoPtDb-vstgMfilr7EoyRDdjOF3EsBE1jzgeUHNDSWe8dVEXrdN2rKCgpBtHFX9F95O7Y3q1qUL-Bk9keiA6Al2soNrZzTf_t_4U_YYKHhw</recordid><startdate>201910</startdate><enddate>201910</enddate><creator>Senosain-Leon, Valeria</creator><creator>Hidalgo-Benites, Aida</creator><creator>Arriola-Montenegro, Jose</creator><creator>D’Angelo-Piaggio, Lorenzo</creator><creator>Beas, Renato</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4092-6601</orcidid></search><sort><creationdate>201910</creationdate><title>Invasive pulmonary aspergillosis with Aspergillus vertebral osteomyelitis in an HIV-infected adult: a case report</title><author>Senosain-Leon, Valeria ; 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After many different diagnostic tests, invasive aspergillosis with pleuroparenchymal involvement and vertebral osteomyelitis by Aspergillus spp. was diagnosed. The patient was treated with amphotericin B deoxycholate without improvement and a fatal outcome ensued. Differential diagnoses of vertebral osteomyelitis in immunosuppressed patients should be taken into account for early detection and prompt treatment.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>31558121</pmid><doi>10.1177/0956462419865403</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0003-4092-6601</orcidid></addata></record> |
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subjects | Adult AIDS/HIV Antiretroviral Therapy, Highly Active Aspergillosis - diagnosis Aspergillosis - immunology Aspergillosis - pathology Aspergillus - isolation & purification Fatal Outcome HIV Infections - complications HIV Infections - drug therapy Humans Immunocompromised Host Invasive Pulmonary Aspergillosis Magnetic Resonance Imaging Male Opportunistic Infections - complications Opportunistic Infections - microbiology Osteomyelitis - complications Osteomyelitis - diagnosis Osteomyelitis - microbiology |
title | Invasive pulmonary aspergillosis with Aspergillus vertebral osteomyelitis in an HIV-infected adult: a case report |
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