Detection of tBid Oligomerization and Membrane Permeabilization by Graphene-Based Single-Molecule Surface-Induced Fluorescence Attenuation

The permeabilization of organelle membranes by BCL-2 family proteins is a pivotal step during the regulation of apoptosis; the underlying mechanisms remain unclear. Based on the fluorescence attenuation by graphene oxide, we developed a single-molecule imaging method termed surface-induced fluoresce...

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Veröffentlicht in:Nano letters 2019-10, Vol.19 (10), p.6937-6944
Hauptverfasser: Ma, Li, Hu, Shuxin, He, Xiaolong, Yang, Na, Chen, Licui, Yang, Chenguang, Ye, Fangfu, Wei, Taotao, Li, Ming
Format: Artikel
Sprache:eng
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