A comparative study of viscoelasticity between normal cornea and keratoconus
Study of the mechanical properties of in vivo corneal materials is an important basis for further study of corneal physiological and pathological phenomena by means of finite element method. In this paper, the elastic coefficient ( ) and viscous coefficient ( ) of normal cornea and keratoconus under...
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| Veröffentlicht in: | Sheng wu yi xue gong cheng xue za zhi 2019-08, Vol.36 (4), p.613 |
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| container_title | Sheng wu yi xue gong cheng xue za zhi |
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| creator | Zhao, Kechao Wang, Xiaojun Chen, Weiyi He, Rui Li, Xiaona Gao, Yan |
| description | Study of the mechanical properties of in vivo corneal materials is an important basis for further study of corneal physiological and pathological phenomena by means of finite element method. In this paper, the elastic coefficient (
) and viscous coefficient (
) of normal cornea and keratoconus under pulse pressure are calculated by using standard linear solid model with the data provided by corneal visualization scheimpflug technology. The results showed that there was a significant difference of
and
between normal cornea and keratoconus cornea (
< 0.05). Receiver operating characteristic curve analysis showed that the area under curve (AUC) for
,
and their combined indicators were 0.776, 0.895 and 0.948, respectively, which indicated that keratoconus could be predicted by
and
. The results of this study may provide a reference for the early diagnosis of keratoconus and avoid the occurrence of keratoconus after operation, so it has a certain clinical value. |
| doi_str_mv | 10.7507/1001-5515.201812052 |
| format | Article |
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) and viscous coefficient (
) of normal cornea and keratoconus under pulse pressure are calculated by using standard linear solid model with the data provided by corneal visualization scheimpflug technology. The results showed that there was a significant difference of
and
between normal cornea and keratoconus cornea (
< 0.05). Receiver operating characteristic curve analysis showed that the area under curve (AUC) for
,
and their combined indicators were 0.776, 0.895 and 0.948, respectively, which indicated that keratoconus could be predicted by
and
. The results of this study may provide a reference for the early diagnosis of keratoconus and avoid the occurrence of keratoconus after operation, so it has a certain clinical value.</description><identifier>ISSN: 1001-5515</identifier><identifier>DOI: 10.7507/1001-5515.201812052</identifier><identifier>PMID: 31441262</identifier><language>chi</language><publisher>China</publisher><subject>Area Under Curve ; Cornea - physiology ; Elasticity ; Humans ; Keratoconus - pathology ; ROC Curve ; Viscosity</subject><ispartof>Sheng wu yi xue gong cheng xue za zhi, 2019-08, Vol.36 (4), p.613</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31441262$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhao, Kechao</creatorcontrib><creatorcontrib>Wang, Xiaojun</creatorcontrib><creatorcontrib>Chen, Weiyi</creatorcontrib><creatorcontrib>He, Rui</creatorcontrib><creatorcontrib>Li, Xiaona</creatorcontrib><creatorcontrib>Gao, Yan</creatorcontrib><title>A comparative study of viscoelasticity between normal cornea and keratoconus</title><title>Sheng wu yi xue gong cheng xue za zhi</title><addtitle>Sheng Wu Yi Xue Gong Cheng Xue Za Zhi</addtitle><description>Study of the mechanical properties of in vivo corneal materials is an important basis for further study of corneal physiological and pathological phenomena by means of finite element method. In this paper, the elastic coefficient (
) and viscous coefficient (
) of normal cornea and keratoconus under pulse pressure are calculated by using standard linear solid model with the data provided by corneal visualization scheimpflug technology. The results showed that there was a significant difference of
and
between normal cornea and keratoconus cornea (
< 0.05). Receiver operating characteristic curve analysis showed that the area under curve (AUC) for
,
and their combined indicators were 0.776, 0.895 and 0.948, respectively, which indicated that keratoconus could be predicted by
and
. The results of this study may provide a reference for the early diagnosis of keratoconus and avoid the occurrence of keratoconus after operation, so it has a certain clinical value.</description><subject>Area Under Curve</subject><subject>Cornea - physiology</subject><subject>Elasticity</subject><subject>Humans</subject><subject>Keratoconus - pathology</subject><subject>ROC Curve</subject><subject>Viscosity</subject><issn>1001-5515</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMFLwzAYxXNQ3Jj7CwTJ0Utn8iVpk-MY6oSCl91Lkn6BYtvUpp3sv7fg9PTg8X6PxyPkgbNdoVjxzBnjmVJc7YBxzYEpuCHrf3dFtik1jjHQLM-1uCMrwaXkkMOalHvqYzfY0U7NGWma5vpCY6DnJvmIrU1T45vpQh1O34g97ePY2XZhxh4ttX1NP3Fho4_9nO7JbbBtwu1VN-T0-nI6HLPy4-39sC-zQeWQaWOkQwxM1sY5x5nNhXCBeVcXRhXBCOllcAZrKQQE5X3BuWegDGgNXIsNefqtHcb4NWOaqm5Zi21re4xzqgCM5rKAXC7Rx2t0dh3W1TA2nR0v1d8B4geGNVzN</recordid><startdate>20190825</startdate><enddate>20190825</enddate><creator>Zhao, Kechao</creator><creator>Wang, Xiaojun</creator><creator>Chen, Weiyi</creator><creator>He, Rui</creator><creator>Li, Xiaona</creator><creator>Gao, Yan</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20190825</creationdate><title>A comparative study of viscoelasticity between normal cornea and keratoconus</title><author>Zhao, Kechao ; Wang, Xiaojun ; Chen, Weiyi ; He, Rui ; Li, Xiaona ; Gao, Yan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p562-8994beef04d9bbb10a633bf0cbd7957f934c4fb9ed4332f5cc711c02592882183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2019</creationdate><topic>Area Under Curve</topic><topic>Cornea - physiology</topic><topic>Elasticity</topic><topic>Humans</topic><topic>Keratoconus - pathology</topic><topic>ROC Curve</topic><topic>Viscosity</topic><toplevel>online_resources</toplevel><creatorcontrib>Zhao, Kechao</creatorcontrib><creatorcontrib>Wang, Xiaojun</creatorcontrib><creatorcontrib>Chen, Weiyi</creatorcontrib><creatorcontrib>He, Rui</creatorcontrib><creatorcontrib>Li, Xiaona</creatorcontrib><creatorcontrib>Gao, Yan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Sheng wu yi xue gong cheng xue za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhao, Kechao</au><au>Wang, Xiaojun</au><au>Chen, Weiyi</au><au>He, Rui</au><au>Li, Xiaona</au><au>Gao, Yan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparative study of viscoelasticity between normal cornea and keratoconus</atitle><jtitle>Sheng wu yi xue gong cheng xue za zhi</jtitle><addtitle>Sheng Wu Yi Xue Gong Cheng Xue Za Zhi</addtitle><date>2019-08-25</date><risdate>2019</risdate><volume>36</volume><issue>4</issue><spage>613</spage><pages>613-</pages><issn>1001-5515</issn><abstract>Study of the mechanical properties of in vivo corneal materials is an important basis for further study of corneal physiological and pathological phenomena by means of finite element method. In this paper, the elastic coefficient (
) and viscous coefficient (
) of normal cornea and keratoconus under pulse pressure are calculated by using standard linear solid model with the data provided by corneal visualization scheimpflug technology. The results showed that there was a significant difference of
and
between normal cornea and keratoconus cornea (
< 0.05). Receiver operating characteristic curve analysis showed that the area under curve (AUC) for
,
and their combined indicators were 0.776, 0.895 and 0.948, respectively, which indicated that keratoconus could be predicted by
and
. The results of this study may provide a reference for the early diagnosis of keratoconus and avoid the occurrence of keratoconus after operation, so it has a certain clinical value.</abstract><cop>China</cop><pmid>31441262</pmid><doi>10.7507/1001-5515.201812052</doi></addata></record> |
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| issn | 1001-5515 |
| language | chi |
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| source | MEDLINE; PubMed Central |
| subjects | Area Under Curve Cornea - physiology Elasticity Humans Keratoconus - pathology ROC Curve Viscosity |
| title | A comparative study of viscoelasticity between normal cornea and keratoconus |
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