Preclinical Evaluation of a Fluorine-18 (18F)-Labeled Phosphatidylinositol 3‑Kinase Inhibitor for Breast Cancer Imaging

Breast cancer is one of the commonest malignancies in women, especially in middle-aged and elderly women. Abnormal activation of the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKt/mTOR) pathway has been found to be involved in breast cancer proliferation. Pict...

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Veröffentlicht in:Molecular pharmaceutics 2019-11, Vol.16 (11), p.4563-4571
Hauptverfasser: Altine, Bouhari, Gai, Yongkang, Han, Na, Jiang, Yaqun, Ji, Hao, Fang, Hanyi, Niyonkuru, Alexandre, Bakari, Khamis Hassan, Rajab Arnous, Maher Mohamad, Liu, Qingyao, Zhang, Yongxue, Lan, Xiaoli
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Sprache:eng
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