Pregnancy Enables Expansion of Disease-Specific Regulatory T Cells in an Animal Model of Multiple Sclerosis

Disease activity of autoimmune disorders such as multiple sclerosis and its mouse model experimental autoimmune encephalomyelitis (EAE) is temporarily suppressed by pregnancy. However, whether disease amelioration is due to nonspecific immunomodulation or mediated by Ag-specific regulation of diseas...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 2019-10, Vol.203 (7), p.1743-1752
Hauptverfasser:	Engler, Jan Broder, Heckmann, Nina F, Jäger, Jan, Gold, Stefan M, Friese, Manuel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoantigens - genetics Autoantigens - immunology Encephalomyelitis, Autoimmune, Experimental - genetics Encephalomyelitis, Autoimmune, Experimental - immunology Encephalomyelitis, Autoimmune, Experimental - pathology Female Mice Mice, Inbred BALB C Multiple Sclerosis - genetics Multiple Sclerosis - immunology Multiple Sclerosis - pathology Pregnancy Pregnancy Complications - immunology Pregnancy Complications - pathology Receptors, Antigen, T-Cell, alpha-beta - genetics Receptors, Antigen, T-Cell, alpha-beta - immunology T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!